Pat Mayo's 2025 Updated Week 5 Fantasy Football Rankings, Player Notes and NFL Injuries

Oct 01, 2025

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Fantasy Football Week 5 Rankings (1/2 PPR)

Mayo, Jake Ciely & Ian Hartitz break down everything you need to set your best lineup and win your matchup as they debate the Fantasy Football Week 5 Rankings by position: From player rankings to sleeper calls, to trade targets.

WATCH: Week 5 Rankings Debate | Start Sit Advice, Sleepers & Trade Targets

LISTEN ON APPLE: PME WEEK 5 RANKINGS

WATCH/LISTEN ON SPOTIFY: PME WEEK 5 RANKINGS

NOTE: Ranks UPDATED 10/4

Week 5 RB Injuries

Chuba Hubbard (Calf) — OUT
Bucky Irving (Ankle) — OUT
Miles Sanders (Ankle) — Questionable
Tyjae Spears (Ankle) — Questionable
Tyrone Tracy (Shoulder) — Expected OUT
Aaron Jones (Hamstring) — IR; OUT at least 2 More Games
Trey Benson (Knee) — Placed on IR; OUT at least 4 Weeks
Braelon Allen (Knee) — Placed on IR

Week 5 RB Rankings

Omarion Hampton (vs WAS) — WAS is allowing the second fewest RB yards per carry before contact this season. LAC RBs averaging the 9th fewest yards per carry before contact this season. Hampton’s 74.1% gain rate on rushes ranks 30th of 36 qualified RBs. Hampton will need receptions and he’s capable, but WAS allows the second highest opponent aDOT. That’s not where RBs usually win.

Woody Marks (at BAL) — BAL vs RBs (PPR): W1, James Cook (16.8% over expectation) ... W2, CLE RB trio (13.1% over expectation) ... W3, DET RB duo (45.5% over expectation) ... W4, Pacheco (39.7% over expectation). Marks snap share by week: 12.3% - 28.3% - 49.2% - 58.5%. Tiny sample, but 4 qualified RBs average over an air yards per target and over 2.5 yards pr carry after contact: Bijan, CMC, Rhamondre Stevenson, and Marks.

Week 5 WR Injuries

Deebo Samuel (Heel) — Expected IN
Michael Pittman (Hamstring) — Expected IN
Jonathan Mingo (Knee) — Questionable
Calvin Ridley (Knee) — Questionable
Xavier Legette (Hamstring) — Expected IN
Kavontae Turpin (Foot) — OUT
CeeDee Lamb (Ankle) — OUT 1-4 Weeks
Mike Evans (Hamstring) — OUT 1-4 Weeks
Terry McLaurin (Quad) — OUT
Noah Brown (Groin) — OUT
Alec Pierce (Concussion) — OUT
Ricky Pearsall (Knee) — DNP
Jauan Jennings (Ankle/Shoulder) — DNP
Cedric Tillman (Hamstring) — Placed on IR; OUT at least 4 Weeks
Tyreek Hill (Knee) — OUT FOR SEASON
Malik Nabers (Knee) — OUT FOR SEASON
Jalen Coker (Quad) — Practice Window to be Opened
Brandon Aiyuk (Knee) — Practice Window Unlikely to be Opened

Week 5 WR Rankings

Puka Nacua — 42 catches ... Chris Olave is the only other WR with 42+ targets.

Keenan Allen — He and Puka are the only WRs with 5+ catches every week (CMC, McBride, and Ferguson have as well).

Quentin Johnston — Three receivers have multiple games with 23+ PPR points this season: Puka Nacua, Amon-Ra St. Brown, and Johnston.

Parker Washington (MNF, vs KC) —Washington leads JAX in percentage of targets that come 15+ yards down field (38.9%) and the Chiefs own the 7th highest opponent aDOT this season. KC ranks 6th in pressure rate. Lawrence ranks 6th in aDOT when pressured this season and owns the 5th greatest difference in aDOT when pressured compared to when he’s not. Washington was sub 25% snap share in Weeks 1-2, he’s been north of 70% in each of the past two weeks.

Week 5 Props & Sharp Stack Discount

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Here are the current top early week value props…

Week 5 TE Injuries

Brock Bowers (Knee) — Leaning OUT
Dallas Goedert (Knee) — Expected IN
Taysom Hill (Knee) — Expected IN
Foster Moreau — Expected IN
Michael Mayer (Concussion) — OUT
Will Dissly (Knee) — Leaning IN
Noah Fant (Concussion) — Expected IN
Ja’Tavion Sanders (Ankle) — OUT 1-4 Weeks
George Kittle (Hamstring) — OUT 1-4 Weeks

Week 5 TE Rankings

TE Randomness — No TE has been a top 10 guy in all four weeks. Entering MNF, 28 different TEs have finished a week with at least a share of top 10 honors for the weeks

TNF UNDERDOG

Some quick plays for TNF. Also, with Benson out I played Carter +225 and Knight +1600 any time TD. No clue how that backfield shakes out but it’s vs TEN. Everyone’s live to score.