It was reported the Rams would use a committee approach behind Cooper Kupp and Allen Robinson if Jefferson couldn't go so we'll assume that's the plan at this point. That means a likely combo of Skowronek and Atwell.
LAR WR Cooper Kupp - Week 4 Fantasy Football Outlook
Week 4 at San Francisco 49ers
Cooper Kupp is a monster. He was “contained” last week by the Cardinals, and still wound up with 64 yards from scrimmage and a touchdown on four receptions and one rushing attempt. If that’s a “down” game for Kupp, sign me up.
This week, keep Kupp active against a tough 49ers defense. While the games have been low-scoring in general when the 49ers are involved, Courtland Sutton and Tyler Lockett have both produced solid fantasy lines the last two weeks against the defense, so Kupp should have no trouble getting his. He’s a must-start every week, regardless of matchup.