Pat Mayo's 2025 Week 8 Fantasy Football Rankings, Starts, Sits, Sleepers, Busts

Oct 22, 2025

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Fantasy Football Week 8 Rankings

Pat Mayo, Jake Ciely & Ian Hartitz break down everything you need to set your best lineup and win your matchup. From player rankings to sleeper calls, we’ve got you covered.

Week 8 RB Injuries

Bucky Irving (Ankle) — OUT
Aaron Jones (Hamstring) — Questionable
Breece Hall — Leaning IN
Hassan Haskins (hamstring) — Leaning OUT
Kendre Miller (Knee) — OUT FOR SEASON

Week 8 RB Rankings

Derrick Henry (vs CHI) - The Bears allow the 3rd most yards per carry after contact this season. Henry picked up 3.46 YPC after contact in Week 6 against the Rams prior to the bye (Weeks 2-5: 2.09).

Javonte Williams (at DEN) - Williams ranks as RB4 in terms of red zone fantasy points scored this season ... he draws the league’s best red zone defense (6 TDs allowed on 16 red zone drives).

JK Dobbins (vs DAL) - Dobbins is in a three-way tie atop the league in terms of games with 75+ rushing yards. His five such performances are as many as Jahmyr Gibbs and Derrick Henry have combined for this season.

Week 8 Spread Picks

Mayo, Garion Thorne, and Tim Anderson go game-by-game and make their 2025 Week 8 Spread Picks, Bets, Survivor Picks, and Props. Plus, a mini Cust Corner on towel usage, the best fast food burger, and mailbox questions from Dear Custy.

Week 8 WR Injuries

Chris Godwin (Fibula) — OUT
Nico Collins (Concussion) — Leaning OUT
Christian Kirk (Hamstring) — Leaning OUT
Deebo Samuel (heel) — Leaning IN
Terry McLaurin (Quad) — Leaning IN
Calvin Ridley (Hamstring) — Questionable
Garrett Wilson (Knee) — Questionable
Josh Downs (Concussion) — Questionable
Ricky Pearsall (Knee) — Questionable
Calvin Austin (shoulder) — Questionable
Jaylen Waddle — Questionable
Darius Slayton (hamstring) — Questionable
Christian Watson (knee) — Questionable
Ray-Ray McCloud (Personal) — RELEASED BY ATLANTA; Signed by NYG
Brandon Aiyuk (Knee) — Estimated Week 10 Return

Week 8 WR Rankings

Kayshon Boutte (vs CLE) - Play him when Maye isn’t pressured. Rinse repeat. This isn’t as good a spot as the past two weeks (for the season, CLE is middle of the road in pressure rate), but the splits open up the chance to justify a dart throw. The Browns created pressure at the 7th highest rate in September, but rank 26th in October.

Alec Pierce (vs. TEN) - Pierce’s average touchdown length for his career is 30.5 yards. He faces a Titans defense this week that has allowed 13.9% of deep targets to result in a TD (3rd highest rate, league average: 6.8%).

Week 8 QB Injuries

Jayden Daniels (Hamstring) — Expected OUT
Lamar Jackson (Hamstring) — Leaning IN
Brock Purdy (Toe) — Leaning OUT
Bryce Young (Ankle) — OUT
J.J. McCarthy — OUT; Wentz to Start

Week 8 QB Rankings

Dak Prescott (at DEN) - Dak Prescott has multiple 25+ yard completions in all seven weeks this season. He’s the fourth QB to do that over the past decade (Kyler Murray, Matt Ryan, and Patrick Mahomes twice).

Week 8 TE Injuries

Darren Waller (Pec) — Placed on IR
David Njoku (Knee) — Questionable

Week 8 TE Rankings

Kyle Pitts (vs MIA) - His aDOT is tracking to decline for a third straight season, and opponents facing the Dolphins currently own a league-low 6.2-yard aDOT.

Week 8 DST Rankings

The 49ers and Jets are the only defenses without an INT this season ... The Falcons figure to be aggressive (4th in pressure rate when blitzing, 24th when not) ... The Ravens are allowing five red zone trips per game (4.5 is the most allowed per game for an entire season in the 2000s)