Pat Mayo's 2025 Week 5 Fantasy Football Rankings, Player Notes and NFL Injuries

Oct 01, 2025

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Fantasy Football Week 5 Rankings (1/2 PPR)

Mayo, Jake Ciely & Ian Hartitz break down everything you need to set your best lineup and win your matchup as they debate the Fantasy Football Week 5 Rankings by position: From player rankings to sleeper calls, to trade targets.

WATCH: Week 5 Rankings Debate | Start Sit Advice, Sleepers & Trade Targets

LISTEN ON APPLE: PME WEEK 5 RANKINGS

WATCH/LISTEN ON SPOTIFY: PME WEEK 5 RANKINGS

NOTE: Ranks will get updated Saturday Afternoon. So bookmark and come back

Week 5 RB Injuries

Bucky Irving (Ankle) — Leaning OUT
Trey Benson (Knee) — Placed on IR; OUT at least 4 Weeks
Braelon Allen — Placed on IR; OUT at least 4 Weeks
Miles Sanders (Ankle) — Questionable
Tyjae Spears (Ankle) — Questionable
Tyrone Tracy (Shoulder) — OUT 1-4 Weeks

Week 5 RB Rankings

Omarion Hampton (vs WAS) — WAS is allowing the second-fewest RB yards per carry before contact this season. LAC RBs are averaging the 9th fewest yards per carry before contact this season. Hampton’s 74.1% gain rate on rushes ranks 30th of 36 qualified RBs. Hampton will need receptions, and he’s capable, but WAS allows the second-highest opponent aDOT. That’s not where RBs usually win.

Woody Marks (at BAL) — BAL vs RBs (PPR): W1, James Cook (16.8% over expectation) ... W2, CLE RB trio (13.1% over expectation) ... W3, DET RB duo (45.5% over expectation) ... W4, Pacheco (39.7% over expectation). Marks snap share by week: 12.3% - 28.3% - 49.2% - 58.5%. Tiny sample, but four qualified RBs average over an air yards per target and over 2.5 yards pr carry after contact: Bijan, CMC, Rhamondre Stevenson, and Marks.

Week 5 Spread Picks Cheatsheet

Pat Mayo, Geoff Fienberg, and Tim Anderson go game-by-game and make their 2025 Week 5 Spread Picks, Bets, Survivor Picks, and Props. Plus, a mini Cust Corner on Pre Drinking, Costco Meals, McDonalds Monopoly.

WATCH: NFL Week 5 Spread Picks, Survivor | Cust Corner: Pre Drinking, Costco Meals, McDonalds Monopoly

Week 5 WR Injuries

Ricky Pearsall (Knee) — Leaning OUT (TNF)
Jauan Jennings (Ankle/Shoulder) — Questionable (TNF)
Cedric Tillman (hamstring) — Placed on IR; OUT at least 4 Weeks
Tyreek Hill (Knee) — OUT FOR SEASON
Malik Nabers (Knee) — OUT FOR SEASON
CeeDee Lamb (Ankle) — OUT 1-4 Weeks
Mike Evans (Hamstring) — OUT 1-4 Weeks
Terry McLaurin (Quad) — Likely OUT
Alec Pierce (Concussion) — Leaning IN
Noah Brown (Groin) — Questionable
Xavier Legette (Hamstring) — Questionable

Week 5 WR Rankings

Puka Nacua — 42 catches ... Chris Olave is the only other WR with 42+ targets.

Keenan Allen — He and Puka are the only WRs with 5+ catches every week (CMC, McBride, and Ferguson have as well).

Quentin Johnston — Three receivers have multiple games with 23+ PPR points this season: Puka Nacua, Amon-Ra St. Brown, and Johnston.

Parker Washington (MNF, vs KC) —Washington leads JAX in percentage of targets that come 15+ yards downfield (38.9%), and the Chiefs own the 7th highest opponent aDOT this season. KC ranks 6th in pressure rate. Lawrence ranks 6th in aDOT when pressured this season and owns the 5th greatest difference in aDOT when pressured compared to when he’s not. Washington was sub 25% snap share in Weeks 1-2, he’s been north of 70% in each of the past two weeks.

Week 5 Props & Sharp Stack Discount

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Here are the current top early week value props…

Week 5 TE Injuries

Tyler Higbee (hip) — Questionable (TNF)
Michael Mayer (Concussion) — Questionable
Ja'Tavion Sanders (Ankle) — OUT 1-4 Weeks
Will Dissly (Knee) — Questionable
George Kittle (Hamstring) — OUT 1-4 Weeks
Noah Fant (Concussion) — Questionable

Week 5 TE Rankings

TE Randomness — No TE has been a top 10 guy in all four weeks. Entering MNF, 28 different TEs have finished a week with at least a share of top 10 honors for the weeks

TNF UNDERDOG

Some quick plays for TNF. Also, with Benson out I played Carter +225 and Knight +1600 any time TD. No clue how that backfield shakes out but it’s vs TEN. Everyone’s live to score.