Pat Mayo's UPDATED 2025 Week 17 Fantasy Football Rankings, Starts, Sits, Sleepers, NFL Injury Report, Player Notes

Fantasy Football Week 17 Rankings and NFL Injuries

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Week 17 RB Injuries

• Alvin Kamara (Knee) — OUT

• TreVeyon Henderson — IN

• Dylan Sampson — EXPECTED IN

• Quinshon Judkins (Leg) — OUT FOR SEASON

Week 17 RB Rankings

1. Christian McCaffrey

2. Bijan Robinson

3. Jonathan Taylor

4. Chase Brown

5. De’Von Achane

6. Ashton Jeanty

7. James Cook

8. Saquon Barkley

9. Travis Etienne

10. Bucky Irving

11. TreVeyon Henderson

12. Kenneth Gainwell

13. Jaylen Warren

14. Kyren Williams

15. Tony Pollard

16. D’Andre Swift

17. Kenneth Walker

18. Tyrone Tracy

19. Dylan Sampson

20. Breece Hall

21. Michael Carter

22. Rico Dowdle

23. Rhamondre Stevenson

24. Zach Charbonnet

25. Kyle Monangai

26. Blake Corum

27. Tyjae Spears

28. Chuba Hubbard

29. Tyler Allgeier

30. Devin Singletary

31. Isaiah Davis

32. Samaje Perine

33. Emari Demercado

34. Audric Estime

35. Trayveon Williams

36. Rachaad White

37. Raheim Sanders

38. Ty Johnson

39. Sean Tucker

40. Jaylen Wright

41. Brian Robinson

42. D’Ernest Johnson

43. Evan Hull

44. LeQuint Allen

45. Ameer Abdullah

46. Rasheen Ali

47. Tank Bigsby

48. Kyle Juszczyk

49. Ollie Gordon

50. Brashard Smith

51. Corey Kiner

52. Ray Davis

53. DeeJay Dallas

54. Andrew Beck

Ashton Jeanty vs NYG — The Giants allow a league-high 3.78 yards per carry after first contact to RBs this season (24.1% worse than league average). This season, 84.9% of Jeanty’s rush yards have come after contact.

Tony Pollard vs NO —Pollard is the only non-AFC East running back with three consecutive 100-rush yard games this season (the Saints rank 24th in success rate against RBs this season).

Week 17 Best Bets

Pat Mayo, Rob Pizzola, and Cam Stewart break down the full 2025 NFL Week 17 slate, with betting analysis, game previews, and our favorite teaser plays. Whether you’re looking for sharp betting edges, insights on key matchups, or value picks, this Week 17 betting guide has you covered.

• WATCH: NFL Week 17 Best Bets, Teasers, Props | 2025 NFL Picks & Game Previews

• LISTEN ON APPLE

• WATCH/LISTEN ON SPOTIFY

Week 17 WR Injuries

• Rome Odunze (Foot) — OUT

• DK Metcalf (Suspension) — OUT

• Davante Adams (Hamstring) — Leaning OUT

• DeMario Douglas (hamstring) — Leaning OUT

• Kayshon Boutte (Concussion) — OUT

• Mack Hollins (7-Minute Abs) — OUT

• Calvin Austin (316) — OUT

• DeMario Douglas (Hamstring) —Leaning OUT

• Luther Burden (ankle) — Leaning IN

• Ricky Pearsall (knee) — Questionable

Week 17 WR Rankings

1. Puka Nacua

2. Ja’Marr Chase

3. Jaxon Smith-Njigba

4. Chris Olave

5. Jauan Jennings

6. Drake London

7. D.J. Moore

8. Mike Evans

9. Tee Higgins

10. A.J. Brown

11. Jakobi Meyers

12. Stefon Diggs

13. Jaylen Waddle

14. Tetairoa McMillan

15. Chris Godwin

16. Wan’Dale Robinson

17. DeVonta Smith

18. Brian Thomas Jr.

19. Michael Wilson

20. Adonai Mitchell

21. Alec Pierce

22. Marvin Harrison Jr.

23. Luther Burden

24. Parker Washington

25. Michael Pittman Jr.

26. Tre Tucker

27. Darius Slayton

28. Jalen Coker

29. Khalil Shakir

30. Emeka Egbuka

31. Rashid Shaheed

32. Kyle Williams

33. Jack Bech

34. Olamide Zaccheaus

35. Josh Downs

36. Elic Ayomanor

37. Cooper Kupp

38. Chimere Dike

39. Jerry Jeudy

40. John Metchie

41. Darnell Mooney

42. Kendrick Bourne

43. Malik Washington

44. Isaiah Bond

45. Xavier Legette

46. Isaiah Williams

47. Tyler Lockett

48. Konata Mumpfield

49. Mason Tipton

50. Andrei Iosivas

51. Joshua Palmer

52. Xavier Smith

53. Christian Kirk

54. Cedric Tillman

55. Van Jefferson

56. Kevin Austin

57. Tyrell Shavers

58. Jahdae Walker

59. Marquez Valdes-Scantling

Wan’Dale Robinson at LV — Robinson has earned at least 30% of the targets in six of seven games and the Raiders allow the second highest opponent completion percentage this season (68.9%).

Week 17 Spread Picks

Mayo, Geoff Fienberg and Tim Anderson go game-by-game and make their 2025 Week 17 Spread Picks, Bets, Survivor Picks, and chat all things NFL. Plus, a mini Cust Corner on Retirement Plans and Ways to Vacation.

• WATCH: NFL Week 17 Spread Picks, Survivor + Cust Corner

• LISTEN ON APPLE

• WATCH/LISTEN ON SPOTIFY

Week 17 TE Injuries

• David Njoku (knee) — OUT

• Mason Taylor (Neck) — OUT

• Theo Johnson (illness) — OUT

• Harold Fannin (Groin) — Leaning IN

• George Kittle (Ankle) — Questionable

• Noah Fant — Questionable

• Brock Bowers (Knee) — OUT FOR SEASON

Week 17 TE Rankings

1. Trey McBride

2. Harold Fannin

3. Juwan Johnson

4. George Kittle

5. Kyle Pitts

6. Hunter Henry

7. Brenton Strange

8. Taysom Hill

9. Tyler Warren

10. Colston Loveland

11. Dallas Goedert

12. Darren Waller

13. Mike Gesicki

14. Colby Parkinson

15. AJ Barner

16. Dalton Kincaid

17. Cole Kmet

18. Chigoziem Okonkwo

19. Gunnar Helm

20. Pat Freiermuth

21. Greg Dulcich

22. Dawson Knox

23. Terrance Ferguson

24. Cade Otton

Hunter Henry at NYJ — The Jets allow the fifth most red zone drives per game this season: Hunter Henry leads the Patriots with a 33.3% red zone target share.

2026 ONE AND DONE CONTEST

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The Sentry has been cancelled this year, so there won’t be a tournament to remind you to sign up for the following week. So, just reserve your spot right now as not to forget.

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JOIN THE MAYO CUP ONE & DONE CONTEST

Week 17 QB Injuries

• Josh Allen (Foot) - IN

Week 17 QB Rankings

1. Josh Allen

2. Drake Maye

3. Brock Purdy

4. Trevor Lawrence

5. Joe Burrow

6. Jalen Hurts

7. Jacoby Brissett

8. Matthew Stafford

9. Baker Mayfield

10. Caleb Williams

11. Jaxson Dart

12. Tyler Shough

13. Sam Darnold

14. Geno Smith

15. Kirk Cousins

16. Cam Ward

17. Philip Rivers

18. Aaron Rodgers

19. Josh Johnson

20. Quinn Ewers

21. Bryce Young

22. Shedeur Sanders

23. Brady Cook

24. Chris Oladokun

Matthew Stafford at ATL — Stafford has 22 pass TDs on short passes, 10 more than any other QB this season: since Week 6, the Falcons rank 27th in YPA allowed on those short passes.

Tyler Shough at TEN — Shough leads the NFL in yards per touchdown pass this season (24.3) and the Titans allow the third highest average opponent depth of throw.

Week 17 DST Rankings

1. DEN

2. NE

3. SEA

4. LAR

5. PIT

6. JAC

7. NO

8. CLE

9. NYG

10. TB

11. SF

12. TEN

13. CIN

14. LV

The Seahawks create pressure on 53.3% of their blitzes, the second highest rate in the NFL (Bryce Young: 29th of 35 qualified QBs in passer rating vs the blitz this season) ... Just 2.2% of deep passes vs LAC result in a TD, the lowest rate in the league and well below the league average of 7% ... The Panthers allow the third most RB yards per carry before contact and face a Kenneth Walker that is finally trending up ... Two of the better defenses (Texans and Patriots) are the only teams this season to allow a TD on 100% of opponent drives that advance to a goal-to-goal situation