Pat Mayo's UPDATED 2025 Week 17 Fantasy Football Rankings, Starts, Sits, Sleepers, NFL Injury Report, Player Notes

Fantasy Football Week 17 Rankings and NFL Injuries

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Week 17 RB Injuries

• Kimani Vidal (Neck) — Leaning OUT

• Woody Marks (Ankle) — Expected IN

• Alvin Kamara (Knee) — OUT

• TreVeyon Henderson — Questionable

• Dylan Sampson — Questionable

• Quinshon Judkins (Leg) — OUT FOR SEASON

Week 17 RB Rankings

1. Christian McCaffrey

2. Bijan Robinson

3. Jonathan Taylor

4. Chase Brown

5. De’Von Achane

6. Ashton Jeanty

7. James Cook

8. Saquon Barkley

9. Travis Etienne

10. Derrick Henry

11. RJ Harvey

12. Omarion Hampton

13. Bucky Irving

14. TreVeyon Henderson

15. Kenneth Gainwell

16. Jaylen Warren

17. Kyren Williams

18. Tony Pollard

19. D’Andre Swift

20. Kenneth Walker

21. Tyrone Tracy

22. Dylan Sampson

23. Breece Hall

24. Michael Carter

25. Rico Dowdle

26. Woody Marks

27. Rhamondre Stevenson

28. Zach Charbonnet

29. Josh Jacobs

30. Kyle Monangai

31. Blake Corum

32. Tyjae Spears

33. Chuba Hubbard

34. Emanuel Wilson

35. Tyler Allgeier

36. Devin Singletary

37. Isaiah Davis

38. Samaje Perine

39. Emari Demercado

40. Audric Estime

41. Trayveon Williams

42. Rachaad White

43. Raheim Sanders

44. Keaton Mitchell

45. Ty Johnson

46. Jawhar Jordan

47. Sean Tucker

48. Nick Chubb

49. Hassan Haskins

50. Jaylen Wright

51. Brian Robinson

52. D’Ernest Johnson

53. Evan Hull

54. LeQuint Allen

55. Ameer Abdullah

56. Rasheen Ali

57. Tank Bigsby

58. Kyle Juszczyk

59. Ollie Gordon

60. Brashard Smith

61. Corey Kiner

62. Ray Davis

63. DeeJay Dallas

64. Andrew Beck

Omarion Hampton vs HOU — 31% snap share in his Week 14 return from injury, 37.1% in Week 15, and 53.2% in Week 16 with Kimani Vidal ailing. Across those games, he has 10 red zone touches.

Ashton Jeanty vs NYG — The Giants allow a league-high 3.78 yards per carry after first contact to RBs this season (24.1% worse than league average). This season, 84.9% of Jeanty’s rush yards have come after contact.

Derrick Henry at GB — Henry’s gain rate is 93.1% over the past two weeks (prior: 81.5%).

Tony Pollard vs NO —Pollard is the only non-AFC East running back with three consecutive 100-rush yard games this season (the Saints rank 24th in success rate against RBs this season).

Week 17 Best Bets

Pat Mayo, Rob Pizzola, and Cam Stewart break down the full 2025 NFL Week 17 slate, with betting analysis, game previews, and our favorite teaser plays. Whether you’re looking for sharp betting edges, insights on key matchups, or value picks, this Week 17 betting guide has you covered.

• WATCH: NFL Week 17 Best Bets, Teasers, Props | 2025 NFL Picks & Game Previews

• LISTEN ON APPLE

• WATCH/LISTEN ON SPOTIFY

Week 17 WR Injuries

• Rome Odunze (Foot) — OUT

• DK Metcalf (Suspension) — OUT

• Davante Adams (Hamstring) — Leaning OUT

• DeMario Douglas (hamstring) — Leaning OUT

• Kayshon Boutte (Concussion) — OUT

• Mack Hollins (7-Minute Abs) — OUT

• Calvin Austin (316) — OUT

• DeMario Douglas (Hamstring) —Leaning OUT

• Luther Burden (ankle) — Leaning IN

• Ricky Pearsall (knee) — Questionable

Week 17 WR Rankings

1. Puka Nacua

2. Ja’Marr Chase

3. Jaxon Smith-Njigba

4. Chris Olave

5. Jauan Jennings

6. Drake London

7. D.J. Moore

8. Nico Collins

9. Mike Evans

10. Tee Higgins

11. A.J. Brown

12. Jakobi Meyers

13. Stefon Diggs

14. Christian Watson

15. Jaylen Waddle

16. Ladd McConkey

17. Tetairoa McMillan

18. Chris Godwin

19. Wan’Dale Robinson

20. DeVonta Smith

21. Zay Flowers

22. Brian Thomas Jr.

23. Michael Wilson

24. Adonai Mitchell

25. Alec Pierce

26. Quentin Johnston

27. Marvin Harrison Jr.

28. Luther Burden

29. Parker Washington

30. Michael Pittman Jr.

31. Tre Tucker

32. Darius Slayton

33. Jalen Coker

34. Khalil Shakir

35. Emeka Egbuka

36. Rashid Shaheed

37. Keenan Allen

38. Jayden Reed

39. Kyle Williams

40. Jack Bech

41. Olamide Zaccheaus

42. Josh Downs

43. Elic Ayomanor

44. Cooper Kupp

45. Chimere Dike

46. Jerry Jeudy

47. John Metchie

48. Romeo Doubs

49. Jayden Higgins

50. Darnell Mooney

51. Kendrick Bourne

52. Malik Washington

53. Isaiah Bond

54. Xavier Legette

55. Isaiah Williams

56. Tyler Lockett

57. Konata Mumpfield

58. Mason Tipton

59. Andrei Iosivas

60. Joshua Palmer

61. Xavier Smith

62. Christian Kirk

63. Cedric Tillman

64. Van Jefferson

65. Kevin Austin

66. Tre’ Harris

67. DeAndre Hopkins

68. Rashod Bateman

69. Tyrell Shavers

70. Dontayvion Wicks

71. Matthew Golden

72. Jahdae Walker

73. Marquez Valdes-Scantling

Wan’Dale Robinson at LV — Robinson has earned at least 30% of the targets in six of seven games and the Raiders allow the second highest opponent completion percentage this season (68.9%).

Week 17 Spread Picks

Mayo, Geoff Fienberg and Tim Anderson go game-by-game and make their 2025 Week 17 Spread Picks, Bets, Survivor Picks, and chat all things NFL. Plus, a mini Cust Corner on Retirement Plans and Ways to Vacation.

• WATCH: NFL Week 17 Spread Picks, Survivor + Cust Corner

• LISTEN ON APPLE

• WATCH/LISTEN ON SPOTIFY

Week 17 TE Injuries

• David Njoku (knee) — OUT

• Mason Taylor (Neck) — OUT

• Theo Johnson (illness) — OUT

• Harold Fannin (Groin) — Leaning IN

• George Kittle (Ankle) — Questionable

• Noah Fant — Questionable

• Brock Bowers (Knee) — OUT FOR SEASON

Week 17 TE Rankings

1. Trey McBride

2. Harold Fannin

3. Juwan Johnson

4. George Kittle

5. Kyle Pitts

6. Hunter Henry

7. Brenton Strange

8. Taysom Hill

9. Tyler Warren

10. Colston Loveland

11. Dallas Goedert

12. Darren Waller

13. Dalton Schultz

14. Mike Gesicki

15. Colby Parkinson

16. AJ Barner

17. Oronde Gadsden

18. Dalton Kincaid

19. Cole Kmet

20. Chigoziem Okonkwo

21. Gunnar Helm

22. Isaiah Likely

23. Pat Freiermuth

24. Greg Dulcich

25. Dawson Knox

26. Terrance Ferguson

27. Cade Otton

Hunter Henry at NYJ — The Jets allow the fifth most red zone drives per game this season: Hunter Henry leads the Patriots with a 33.3% red zone target share.

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Week 17 QB Injuries

• Lamar Jackson (back) — OUT

• Jordan Love (Concussion) — OUT

• Malik Willis (Shoulder) — Expected IN

Week 17 QB Rankings

1. Josh Allen

2. Drake Maye

3. Brock Purdy

4. Trevor Lawrence

5. Joe Burrow

6. Jalen Hurts

7. Jacoby Brissett

8. Matthew Stafford

9. Baker Mayfield

10. Caleb Williams

11. Jaxson Dart

12. Tyler Shough

13. Sam Darnold

14. Justin Herbert

15. Geno Smith

16. C.J. Stroud

17. Kirk Cousins

18. Cam Ward

19. Philip Rivers

20. Malik Willis

21. Aaron Rodgers

22. Tyler Huntley

23. Josh Johnson

24. Quinn Ewers

25. Bryce Young

26. Shedeur Sanders

27. Brady Cook

28. Chris Oladokun

Matthew Stafford at ATL — Stafford has 22 pass TDs on short passes, 10 more than any other QB this season: since Week 6, the Falcons rank 27th in YPA allowed on those short passes.

Tyler Shough at TEN — Shough leads the NFL in yards per touchdown pass this season (24.3) and the Titans allow the third highest average opponent depth of throw.

Week 17 DST Rankings

1. DEN

2. NE

3. HOU

4. SEA

5. LAC

6. LAR

7. PIT

8. JAC

9. NO

10. CLE

11. NYG

12. GB

13. TB

14. SF

15. TEN

16. CIN

17. LV

The Seahawks create pressure on 53.3% of their blitzes, the second highest rate in the NFL (Bryce Young: 29th of 35 qualified QBs in passer rating vs the blitz this season) ... Just 2.2% of deep passes vs LAC result in a TD, the lowest rate in the league and well below the league average of 7% ... The Panthers allow the third most RB yards per carry before contact and face a Kenneth Walker that is finally trending up ... Two of the better defenses (Texans and Patriots) are the only teams this season to allow a TD on 100% of opponent drives that advance to a goal-to-goal situation