WEEK 12 NFL CHEATSHEET

Mayo updates his 2025 Fantasy Football Week 12 rankings with the latest news and goes through the Week 12 NFL Injury Report telling you who is in and out and which players stand to benefit. Mayo then goes through his favorite Week 12 Props and fills out an Underdog Pick’em Entry before getting to his Top Cheap Plays on DraftKings for Week 12 at each position.

WATCH: NFL Week 12 Weekend Cheatsheet: Updated Rankings, Injuries, Player Props | DraftKings Picks Ownership, Values

WEEK 12 NFL INJURIES

Week 12 RB Injuries

• Bucky Irving (Foot/Shoulder) — OUT

• Emari Demercado (Foot) — OUT

• Trey Benson (knee) — OUT

• Isiah Pacheco (knee) — OUT

• Samaje Perine (ankle) — Expected OUT

• Josh Jacobs (knee) — GAME TIME DECISION

• Jaylen Warren (ankle) — IN

• Justice Hill (toe) — IN

• Bhayshul Tuten (Ankle) — IN

• Rhamondre Stevenson (Toe) — IN

UPDATED: WEEK 12 FANTASY FOOTBALL RANKINGS

Week 12 WR Injuries

• Ja’Marr Chase (Suspension) — OUT

• Drake London (Knee) — OUT

• Garrett Wilson (Knee) — OUT

• Marvin Harrison (appendix) — OUT

• Elic Ayomanor (hamstring) — OUT

• Tory Horton (Groin/Shin) — Placed on IR

• Rashod Bateman (ankle) — OUT

• Brian Thomas Jr. (ankle) — OUT

• Kayshon Boutte (Hamstring) — IN

• Chimere Dike (Chest) — IN

• Darius Slayton (Hamstring) — IN

• Chris Godwin (fibula) — Leaning IN

• Calvin Ridley (ankle) — OUT FOR SEASON

Week 12 TE Injuries

• Tyler Higbee (Knee) — Placed on IR

• Mike Gesicki (pec) — Expected IN

• David Njoku (knee) — IN

• Brenton Strange (hip) — Activated; Leaning IN

• Hunter Long (hip/knee) — OUT

• Austin Hooper (concussion) — Expected IN

• Dalton Kincaid (hamstring) — DNP

Week 12 QB Injuries

• Joe Burrow — OUT; Flacco Starting

• Jaxson Dart (concussion) — OUT; Jameis will start

• Michael Penix (knee) — OUT; Likely for Season

• Justin Fields (BAD) — Benched; Tyrod Taylor Will Start

• C.J. Stroud (Concussion) — OUT

• Dillon Gabriel (Concussion) — OUT; Sanders Starting

• Aaron Rodgers (hand) — Leaning IN

WEEK 12 RED ZONE WATCH ALONG!!!!

WE’RE BACK AGAIN for Week 12 Redzone. If you’re looking to hang with someone when Week 12 kicks off, you can do it with me, Cust, and Friends live from MMN HQ.

We’ll be streaming RedZone and talking along over the RZ stream on Playback. Playback has the rights to RedZone, and we’ll be doing commentary while we all watch it together in perfect sync. It’ll be on YouTube as well, but we don’t have the rights to stream RedZone there, so it will just be us talking in the room. Still a good time btw.

SIGN UP FREE FOR PLAYBACK AND WATCH ALONG WITH THE PME CREW

Week 12 Best Bets

Mayo, Rob Pizzola, and Cam Stewart. We break down the full 2025 NFL Week 12 slate, with betting analysis, game previews, and our favorite teaser plays. Whether you’re looking for sharp betting edges, insights on key matchups, or value picks, this Week 12 betting guide has you covered.

WATCH: NFL Week 12 Best Bets, Teasers, Fastest 60s

GOLD

• MAYO: ATL +2.5

• PIZZOLA: DAL +3.5

• CAM: PIT +3

SILVER

• MAYO: SEA -13

• PIZZOLA: LAR -6.5

• CAM: LV -3.5

BRONZE

• MAYO: SF -6.5

• PIZZOLA: IND +3.5

• CAM: ARZ +3

6-POINT GROUP TEASER: PIT +9/IND +9.5/ATL +8.5

• 2025 Teaser Record: 7-4

Week 13 Spread Picks

Mayo, Geoff Fienberg and Tim Anderson go game-by-game and make their 2025 Week 12 Spread Picks, Bets, Survivor Picks, and Props. Plus, a mini Cust Corner on the Easiest Things to do in Sports.

• WATCH: NFL Week 12 Spread Picks, Survivor + Cust Corner

• LISTEN ON APPLE

• WATCH/LISTEN ON SPOTIFY

MAYO: BUF -5.5, PIT +2.5, NE -8, IND +3, MIN +6.5, BAL -13.5, SEA -13.5, NYG +10.5, LV -3, ARZ +2.5, DAL +3.5, ATL +2, LAR -6.5, SF -6.5

GEOFF: BUF -5.5, CHI -2.5, NE -8, IND +3, GB -6.5, NYJ +13.5, SEA -13.5, DET -10.5, LV -3, JAX -2.5, PHI -3.5, NO -2, LAR -6.5, SF -6.5

CUST: BUF -5.5, CHI -2.5, NE -8, KC -3, MIN +6.5, NYJ +13.5, SEA -13.5, DET -10.5, LV -3, ARZ +2.5, PHI -3.5, ATL +2, LAR -6.5, SF -6.5

THE COIN: BUF -5.5, CHI -2.5, CIN +8, KC -3, MIN +6.5, BAL -13.5, TEN +13.5, NYG +10.5, LV -3, JAX -2.5, DAL +3.5, NO -2, LAR -6.5, SF -6.5

2025 RECORD (SEASON RECORD)

• MAYO: 4-11 (76-84)

• GEOFF: 10-5 (88-72)

• CUST: 8-7 (96-64)

• COIN: 7-8 (78-82)

SUPERLOCK (SEASON RECORD)

• MAYO: ATL +2 (2-8)

• GEOFF: SF -6.5 (7-4)

• CUST: KC -3 (5-6)

CUST “FREE MONEY” PICKS

• 6-POINT TEASER: NE -2/SEA -7.5/ATL +8/SF -0.5/DET -3.5

• Cust’s 2025 Record: 2-9

• Cust’s Lifetime Record: 32–161

NFL Week 12 Prop Bets

I’ve worked with my pals at Coolbet to boost a four-player prop parlay. If you’re in Canada (Outside Ontario), I’ll have boosted plays at Coolbet all season long. Highly recommend. TWO THIS WEEK!!!!

Get a the PME Exclusive Boosts at Coolbet

Remember to use the profit boosts in the Underdog lobby to get more value on every entry too! If you’re new to Underdog, code MAYO gets you a deposit bonus, the “Play $5 Get $50 in Bonus Funds to Play $5 Get $100 in Bonus Funds” offer.

TAIL OR FADE + code “MAYO” at underdog for a deposit bonus up to $1000

Week 12 DraftKings Values & Ownership

Mayo, Tyler Tamboline, and John Breslin of 4for4 DFS Fantasy break down the best 2025 NFL Week 12 DraftKings picks, lineups, and DFS strategy to help you build winning rosters. We cover ownership projections, game stacks, top plays, and fades

WATCH: NFL Week 12 DraftKings Picks 2025 | Best DFS NFL Lineups, Ownership Projections

RBs Projected Ownership 18%+

1. Chase Brown

2. Jahmyr Gibbs

3. Bijan Robinson

4. Emanuel Wilson (If Jacobs OUT)

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WR Projected Ownership 18%+

1. Amon-Ra St. Brown

2. Michael Wilson

3. Jakobi Meyers

4. Wan’Dale Robinson

TE Projected Ownership 10%+

1. Trey McBride

2. George Kittle

3. Mark Andrews

QB Projected Ownership 10%+

1. Patrick Mahomes

2. Jacoby Brissett

3. Drake Maye

4. Jalen Hurts

5. Jared Goff

DST Projected Ownership 8%+

1. Browns

2. Saints

3. Raiders

4. Seahawks

WEEK 12 SUNDAY NIGHT LIVE

Cust and I are going LIVE at 715pm ET on MMN Sunday for the INSTA RECAP with Garion Thorne. Join live and guess the Week 12 Spreads along with us and a viewer who is picking with us!

SET A REMINDER AND TUNE IN LIVE!!!!!

Week 12 Cheatsheet… But a different way

FANTASY/INJURY SPIN

🔴 Running Back Chaos

Tampa Bay

• Rachaad White still carries the floor. Expect more Shawn Tucker on the ground vs the Rams’ elite run D, but White should own the passing game.

• Tucker has slight upside, but you’re playing White for 10–12 safe PPR points and a potential goal-line plunge.

Arizona

• Demercado OUT, Trey Benson OUT → It’s Bam Knight SZN.

• Expect a 65/35 split with Michael Carter.

• Bam is a Top 24 RB and the only viable $4K–$5K DK RB this week.

• Fits perfectly if you’re fading the cheap Brissett–McBride–Wilson stack.

Kansas City

• Pacheco OUT.

• Kareem Hunt is TD-or-bust only. Outside top 25. Don’t get cute.

Cincinnati

• Samaje Perine OUT → Wheels up for Chase Brown catches.

• Flacco at QB, Patriots' elite run D → reception funnel incoming.

• Tee Higgins faces Christian Gonzalez → Not the smash spot you may think

Packers

• Josh Jacobs is suddenly trending IN.

• If he plays: Jacobs = low-end RB2; Emmanuel Wilson = RB3/FLEX.

• If Jacobs OUT (early game): Wilson rockets to RB12 and a prime DK value at $5,300

Pittsburgh

• Jaylen Warren IN, but volatile split.

• Bears down 3 LBs → great matchup.

• Rank volatility is sky-high due to the Steelers QB uncertainty. Still start if you’ve got him.

Baltimore

• Justice Hill returns as Henry’s backup, but it is irrelevant.

• Ravens continue expanding Keaton Mitchell as a backup.

Jacksonville

• “King Tut” Bhayshul Tuten IN.

• ETN drops from top 10 to mid RB2.

• Tuten is a desperation FLEX but could steal a TD.

New England

• Stevenson IN, Henderson IN.

• Could be 65/35 either way. Henderson better play, but has no floor with the swing to Stevenson's potential.

Cleveland

• Only play Judkins. Everything else in the passing game is roulette.

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🟠 Wide Receiver & Tight End Notes

Atlanta

• Drake London OUT. Kirk Cousins starting.

• Don’t fall for Casey Washington or David Sills V, aka Fake Kenny Stills.

• Only fringe-flex plays: Mooney, Pitts.

• Bijan or bust.

Jets

• Garrett Wilson OUT.

• A.D. Wilson becomes WR1, but is still too unreliable.

• Best fantasy option: TE Mason Taylor (TE12).

Arizona

• Marvin Harrison OUT again.

• Condensed target tree:
  1. McBride
  2. Michael Wilson
  3. Greg Dortch

Titans

• Calvin Ridley done for season. Dike IN. Xavier Restrepo active as well.

• Don’t start any Titans WRs unless you hate yourself.

Seattle

• Tory Horton placed on IR.

• Between Shaheed and Kupp? Prefer Shaheed as the upside dart.

Baltimore

• Bateman OUT.

• Zay Flowers smash week — receptions or yardage overs both live.

Giants

• Slayton IN. Hyatt expected back to bench.

• Salary saver: Isaiah Hodgins ($3300 DK) still viable.

Tampa Bay

• Chris Godwin is a Sunday Night Football gametime call.
  → Do NOT rely on him this week.

Rams

• Higbee to IR. The remaining Rams TEs are unplayable.

Jaguars

• Brian Thomas OUT again.

• Strange is a late-game GTD at TE. Wouldn’t crack Top 12 if he’s in.

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🟡 Quarterbacks

• Burrow OUT → Flacco IN.

• Jaxon Dart OUT → Jameis IN.

• Michael Penix OUT → Kirk Cousins IN.

• Justin Fields BENCHED → Tyrod IN.

• Shedeur Sanders starting for Cleveland.
  His passing-yard under remains live.

• Aaron Rodgers questionable (hand) but leaning toward playing.
  Even if he does, you’re not starting him — but he’s a small upgrade to Steelers WRs.

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📌 Final DFS Notes

• Best cheap RB: Bam Knight (and honestly the only one worth it).

• Best salary-saving WR: Isaiah Hodgins.

• Best contrarian call: Andrei Iosivas receptions (and $4100 DK).

• Chalk stack still worth riding: Brissett–McBride–Michael Wilson.

BETTING

CoolBet PME Exclusives (Under PME Tab)

1. Seattle -10.5 First Quarter vs Titans (+900)

• Titans can’t move the ball.

• Seattle can move the ball.

• First-quarter blowout script fits perfectly.

2. 5-Leg Player Prop Parlay (+1550)

• Zay Flowers 60+ yards

• Tony Pollard UNDER 40 rushing yards

• Jeanty UNDER 60 rushing yards

• McBride 75+ receiving yards

• Shedeur Sanders UNDER 170 passing yards

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📌 Underdog Pick’em Angles (Code: MAYO)

Mayo’s “spam the board” week with a mix of correlation + boosts.

Seattle First-Quarter Mini Build (2.78x)

• JSN 30+ first-quarter yards

• Pollard UNDER 14.5 first-quarter rush yards

Plays directly into the Seahawks/Titans mismatch.

TAIL OR FADE HERE

Cedric Tillman + Sanders Anti-Correlation

• Tillman OVER 22.5 yards

• Sanders UNDER 159.9 yards

Big plus-juice because if Sanders stinks, Tillman likely benefits.

Yosivas + Chase Brown + Judkins (Boosted to 13.5x)

• Yosivas OVER 3.5 receptions

• Chase Brown OVER 5.5 receptions

• Judkins OVER 1.5 receptions

Use Underdog’s 40–60% boosts .

TAIL OR FADE HERE

Alec Pierce Longest Reception Parlay (6.5x)

• Pierce OVER 25.5 LRP

• Zay Flowers OVER 4.5 receptions

• Saquon UNDER 15.5 receiving yards

Pierce’s longest reception prop has hit 8 of 9 weeks.

TAIL OR FADE HERE

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📌 SharpStack / 4for4 Projections — Best Value Edges

USE CODE “MAYO50” TO GET FREE 7 DAYS OFTHE SHARP STACK BETTING TOOL 50% OFF MONTHLY PRICE

Top Computer Value Bet

JJ McCarthy UNDER 0.5 INT (+160 BETMGM)

• Projection: 0.90 INT

• Best number on the market by 30–40 cents.

• Terrifying sweat, but massive value.

Other Projection-Based Edges

• Kenneth Gainwell UNDER 24.5 rush yards (Bears matchup)

• Friermuth UNDER 20.5 receiving yards

• Mack Hollins UNDER 29.5 yards

• Chris Olave UNDER 5.5 receptions (Fanatics)

• Jonathan Taylor OVER 2.5 receptions (-105 Fanatics)

  • Priced 70 cents better than DraftKings/Pinnacle.

• Mitchell Tinsley (CIN WR3) OVER 10.5 yards (one-catch hit potential)

DFS WEEK 12

🔴 RUNNING BACK: CHAOS SLATE

RB is tight. Value is thin. Most builds start with:

💥 Core Plays

• Jahmyr Gibbs – Best spend-up. 21% ownership isn’t scary. Better TD odds & projection than Jonathan Taylor at $1,700 cheaper.

• Chase Brown – ~30% ownership. Perine out. Perfect pass-game script. Tough run spot, but role > matchup.

• Bam Knight ($4,900) – Best punt RB. ~4% owned. Positive per-dollar value. Prefer him over the Hunt/Gentry tier.

Situational Plays

• TreVeyon Henderson – Ownership cratered to 5% with Stevenson returning.
  Big-field GPP only, but matchup is glorious if he somehow holds the lead role.

• Travis Etienne – Fits nice in the JAX–ARI build. Great comeback option in that stack.

• Bijan Robinson – Sneaking into lineups, but expensive puzzle piece.

• Emanuel Wilson – Only if Jacobs sits; projected ~20% if active. Ownership moves directly to David Montgomery (10% → 17%) if Jacobs plays.

• Derrick Henry – Rotating into a few builds. Solid option.

Overpriced / Difficult Builds

• Jonathan Taylor — $10,000 (!)
  4% ownership for a reason. Nearly impossible to build with him, more so if you want to stack KC options with him.

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🟠 WIDE RECEIVER: WHERE YOU SAVE

It’s far easier to save at WR than RB this week.

Ownership Leaders

• Amon-Ra St. Brown (32%)

• Michael Wilson (22%)

• Jakobi Meyers (20%)

• Wan’Dale Robinson (18–20%)

Mayo Pivots:

• Isaiah Hodgins ($3,300) → Preferred run-back over Wan’Dale even with Slayton returning. Cheap deep TD equity with Winston chucking.

• Christian Watson (7%) → Best low-owned GPP value among the top 5. Vikings can be hit deep.

• Parker Washington ($5,200) → pivot off Meyers.

• Iosivas – Positive value, underpriced, outscores his projection often.

• Alec Pierce / Boutte ($5k) – Cheap deep-shot pair if punting.

Best GPP Values (per the optimizer)

1. Tee Higgins

2. Michael Wilson

3. Amon-Ra Brown

4. DeVonta Smith

5. Christian Watson (best low-owned option)

Also: This is the cheapest the Hurts–A.J. Brown–DeVonta stack will ever be.

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🔵 TIGHT END: THE Trey McBride SLATE

This is simple:

💥 McBride is the best value on the entire slate

• Projects 22 DK points

• Only 22% owned

• Should be $8,000

• Nearly triple the per-dollar value of Kelce

• Works in any build, especially double-TE lineups

If not McBride… it’s ugly

• Cheap game-stack darts: Brock Wright, Mason Taylor, Juwan Johnson

• Mayo strategy: McBride + cheap TE of stack in many builds.

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🟡 QUARTERBACK

Ownership is flat across the top:

Mahomes, Maye, Goff, Brissett, Hurts all 10–12%.
Lawrence just behind.
Lamar Jackson (8%) is the sneaky stack:

→ Lamar + Flowers + Andrews
He’s not running since the injury → passing spike weeks instead.

Winston is viable in catch-up mode with cheap NYG WRs.

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🟣 DEFENSE

Ownership:

• Saints, Lions, Raiders, Browns

Mayo’s preferred D/ST pool

• Saints ($2,500) – Best salary saver

• Browns ($2,900) – Elite spot

• Seahawks ($4,000) – Best play, toughest to afford

• Chiefs ($3,100) – Only 3% owned

• ARI/JAX – Pure leverage if fading that game

• Vikings (2%) – Outdoor game, pressure vs Jordan Love