2025 Week 13 NFL Weekend Cheatsheet: Injuries, Picks, DFS, Props, Weather, Updated Rankings

Nov 29, 2025

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WEEK 13 NFL CHEATSHEET

Mayo updates his 2025 Fantasy Football Week 13 rankings with the latest news and goes through the Week 13 NFL Injury Report telling you who is in and out and which players stand to benefit. Mayo then goes through his favorite Week 13 Props and fills out an Underdog Pick’em Entry before getting to his Top Cheap Plays on DraftKings for Week 13 at each position.

WATCH: NFL Week 13 Weekend Cheatsheet: Updated Rankings, Injuries, Player Props | DraftKings Picks Ownership, Values

WEEK 13 NFL INJURIES

Week 13 RB Injuries

Omarion Hampton (foot) — OUT
Alvin Kamara (Knee) — OUT
Trey Benson (knee) — OUT
Emari Demercado (Foot) — OUT
Bucky Irving (Foot/Shoulder) — Leaning IN
Ashton Jeanty (ankle) — Leaning IN
Zonovan Knight (Knee) — Questionable
Jerome Ford (Hamstring) — Questionable

UPDATED: WEEK 13 FANTASY FOOTBALL RANKINGS

Week 13 WR Injuries

Drake London (Knee) — OUT
Garrett Wilson (Knee) — OUT
Noah Brown (groin) — OUT
Tutu Atwell (Hamstring) — IN
BrIan Thomas Jr. (ankle) — IN
Terry McLaurin (Quad) — Leaning IN
Marvin Harrison Jr. (appendix) — Leaning IN
Chris Olave (back) — Questionable
Elic Ayomanor (hamstring) — Leaning OUT
Jayden Reed (shoulder, foot) — DNP
Matthew Golden (wrist) — DNP
Amon-Ra St. Brown (Ankle) — Expected Out Week 14
Tee Higgins (concussion) — DNP

Week 13 TE Injuries

Noah Gray (concussion) — OUT
Michael Mayer (Ankle) — OUT
Darren Waller (Pec) — Expected to be activated; Leaning IN
Chig Okonkwo (foot) — Leaning IN
Hunter Long (hip/knee) — IN
Dalton Kincaid (hamstring) — Questionable

Week 13 QB Injuries

J.J McCarthy (concussion) — OUT; Brosmer will Start
Daniel Jones (Fibula) — IN
C.J. Stroud (Concussion) — IN
Jaxson Dart (concussion) — IN
Aaron Rodgers (hand) — Expected IN
Baker Mayfield (shoulder) — Expected IN
Jayden Daniels (Elbow) — OUT; Leaning Week 14 Return

Week 13 Best Bets

Mayo, Rob Pizzola, and Cam Stewart. We break down the full 2025 NFL Week 13 slate, with betting analysis, game previews, and our favorite teaser plays. Whether you’re looking for sharp betting edges, insights on key matchups, or value picks, this Week 13 betting guide has you covered.

WATCH: NFL Week 13 Best Bets, Teasers, Fastest 60s

GOLD

MAYO: IND -4
PIZZOLA: WAS +6
CAM: LV +10

SILVER

MAYO: ARZ +3
PIZZOLA: CLE +5.5
CAM: BUF -3

BRONZE

MAYO: NYG +7.5
PIZZOLA: LAR -9.5
CAM: NYJ +2.5

6-POINT GROUP TEASER: ARZ +9/NYJ +8.5/NE -1.5

2025 Teaser Record: 8-4

Week 13 Spread Picks

Mayo, Geoff Fienberg, and Tim Anderson go game-by-game and make their 2025 Week 13 Spread Picks, Bets, Survivor Picks, and Props. Plus, a mini Cust Corner on the funniest comedy movies of all time.

WEEK 13 NFL PICKS CHEATSHEET

MAYO: DET -2.5, DAL +3, BAL -7, CHI +6.5, IND -4, CLE +6, JAX -6.5, NO +5.5, NYJ +2.5, ARZ +2.5, CAR +10, BUF -3.5, MIN +10, LV +9.5, DEN -6.5, NYG +7.5

GEOFF: GB +2.5, KC -3, BAL -7, PHI -6.5, HOU +4, CLE +6, TEN +6.5, NO +5.5, ATL -2.5, ARZ +2.5, CAR +10, BUF -3.5, SEA -10, LV +9.5, DEN -6.5, NYG +7.5

CUST: DET -2.5, DAL +3, BAL -7, PHI -6.5, HOU +4, SF -6, JAX -6.5, MIA -5.5, ATL -2.5, ARZ +2.5, LAR -10, PIT +3.5, MIN +10, LAC -9.5, DEN -6.5, NE -7.5

THE COIN: DET -2.5, KC -3, BAL -7, PHI -6.5, IND -4, SF -6, JAX -6.5, NO +5.5, NYJ +2.5, TB -2.5, CAR +10, PIT +3.5, SEA -10, LAC -9.5, WAS +6.5, NE -7.5

2025 RECORD (SEASON RECORD)

MAYO: 5-8 (81-92)
GEOFF: 6-7 (94-79)
CUST: 5-8 (101-72)
COIN: 8-5 (86-87)

SUPERLOCK (SEASON RECORD)

MAYO: IND -4 (3-8)
GEOFF: ARZ +2.5 (7-4)
CUST: DEN -6.5 (5-6)

CUST “FREE MONEY” PICKS

6-POINT TEASER: SF PK/ARZ+8.5/LAC -3.5/DEN -0.5
Cust’s 2025 Record: 2-11
Cust’s Lifetime Record: 32-163

NFL Week 13 Prop Bets

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Week 13 DraftKings Values & Ownership

RBs Projected Ownership 18%+

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WR Projected Ownership 18%+

TE Projected Ownership 10%+

QB Projected Ownership 10%+

DST Projected Ownership 8%+

WEEK 13 SUNDAY NIGHT LIVE

Cust and I are going LIVE at 715pm ET on MMN Sunday for the INSTA RECAP with Garion Thorne. Join live and guess the Week 14 Spreads along with us and a viewer who is picking with us!

SET A REMINDER AND TUNE IN LIVE!!!!!

Week 13 Cheatsheet… But a different way

FANTASY/INJURY SPIN

🔋 Running Back Roulette (aka, Why Do We Play This Game?)

Chargers Backfield

Omarion Hampton activated… but not playing. Cool. Thanks.
Kamani Vidal gets the full go against the Raiders. Fire him up — probably 18 touches.

Saints Backfield

Alvin Kamara? OUT.
Welcome to Devin “Dinosaur Neil” Week.
Is he good? No. Is he playable? Sure. But volume is volume, and Taysom Hill is probably going to appear out of a fog and steal every TD chance
RB2 volume play: Neil.

Cardinals Dumpster Fire

Trey Benson? OUT.
Demercado? OUT.
So it’s Bam Knight, except… BAM KNIGHT IS ALSO HURT.
New Thursday knee issue. Might play, might explode into dust on his first carry vs Tampa’s elite run D.

Plays I like here:

Michael Carter overs on receptions
Bam Knight UNDER on rushing yards
Prayers

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⚡️ Bucs RB Gong Show

“Hot hand,” says the coach. Translation: “We have no idea who is playing or why.”
Bucky Irving → best player, best start.
Sewan Tucker → Meh+
Rachaad White → the “ehhh” option if this truly becomes a three-headed mess.

My take:
Start Irving as a mid-RB2, sit the rest unless you’re into stress-induced aging.

☠️ Cleveland Backfield Misery

Jerome Ford → hamstring, might not play.
Bad weather game, tons of rushing.
If Ford sits:

Judkins = main guy
Dylan Sampson = passing downs

🟦 WIDE RECEIVER CHAOS REPORT

Out or Basically Out

Back / Expected Back

Terry McLaurin
Deebo
Tutu Atwell
BrIan Thomas
Jaylen Lane

The Big One: Marvin Harrison Jr.

Limited practice all week. Trending toward playing.
Great!
Unless you’re Michael Wilson. RIP to your elite fantasy hopes.

Cardinals vs Tampa = pass funnel
Play McBride, Harrison, Wilson (in that order).
Both top-30 WRs.

Chris Olave Watch

Back spasms. Supposed to play.
Could scratch last minute.
If he’s in, you play him.
If he’s out, it’s the Mason Tipton experience — which you absolutely do not want.

Titans WRs

Elic Ayomanor → hamstring, leaning OUT
Dike should be the dude again.
But if you’re starting Titans WRs, something has gone very wrong in your life.

🔒 TIGHT END STUFF NO ONE WANTS TO THINK ABOUT

Brock Bowers — wheels up.
Mayer OUT Ian Thomas — Sneaky overs if lines are low (1.5 catches, 10ish yards).
Chig Okonkwo — trending in.
Darren Waller — ACTIVATED!!! Should return. Only play if you love sadness or desperately need a TD-or-bust option.
Dalton Kincaid — hamstring, limited all week. Watch actives/inactives Sunday at 11:30am ET.

🧠 QUARTERBACK DISASTER REPORT

JJ McCarthy → OUT. Brosmer starting for Minnesota. 11.5-point dogs. Woof.
Daniel Jones — playing with a cracked fibula
C.J. Stroud — PLAYING
Jackson Dart — Playing MNF.
Aaron Rodgers — Expected to play.
Baker Mayfield — Trending in even with a destroyed shoulder.
Jayden Daniels — out this week, leaning toward Week 14 return.

WEATHER GAMES

All right, before we dive into the props, let’s talk WEATHER, because Week 13 is basically a meteorological middle finger to your fantasy lineup.

🌨️ Cleveland – The Arctic Hellscape

Total is already a measly 35, and guess what?
The books already baked the weather into the lines.
Stop triple-docking every projection because you saw a snow emoji. It’s accounted for.

Still:

Freezing temps
Wind
Precipitation
Cleveland’s defense at home (the actual Thanos of the NFL)

This is a “run the ball 60 times and pray” game. Don’t expect fireworks. Expect sadness.

🌧️ Other Weather Dumps

Jets: Cold rain, light wind → gross
Pittsburgh: Jets weather copy-pasted
Washington SNF: Cold
Monday Night (NE game): BELOW freezing

RULE OF THE WEEK:
Dome game vs bad weather game? Take the dome.
If it’s a coin flip start/sit, choose the guy playing indoors and move on with your life.

🎯 MAYO’S FAVORITE PROPS OF THE WEEK

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Plus, they’ve got a 30% and 60% profit boost right now.
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🟩 Christian McCaffrey – THE DOUBLE DIP SPECIAL

Lower than 69.5 rushing yards
Cleveland = #1 run defense
It’s basically a brick wall wearing shoulder pads.

Higher than 18.5 rushing attempts
Because San Fran is gonna run him straight into said brick wall 20+ times anyway.
The math checks out.

I also like Over 4.5 receptions, but I kept the slip clean.

🟩 Cam Ward – MONEY MAN

Since Mike McCoy took over as OC, Cam Ward is running like someone told him QB kneels were illegal.

Higher than 12.5 rushing yards (This was 8.5 earlier in the week — RIP that number.)
Higher than 33.5 passing attempts
Six of the last seven games, he’s smashed this if they trail, and they’re 6-point dogs.

Cam Ward is quietly turning into one of the best garbage-time kings in the league.

🟧 EARLY WEEK PLAYS I STILL LIKE

Cam Ward over 8.5 rush (if you got it earlier). up to 12.5
McCaffrey under 68.5 rush (number moved, still fine but not as pretty)
Lockett over 28.5 receiving
Keenan Allen under 40.5 receiving
- Oronde Gadsden has nuked his usage every single week.

🎲 THE “SAME GAME MAYO MIXER”

Brock Purdy under 207.5 passing yards
Quinshon Judkins over 18.5 rushing attempts
Christian McCaffrey over 4.5 receptions

Payout: 5.76-to-1
Not the craziest multiplier, but extremely live.

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🔍 SHARPSTACK LIVE EV PLAYS (REAL TIME)

A few of the top EV picks popping right now:

Unders the Computer Likes:

Kyren Williams under 69.5 rushing yards
(I hate it personally, but math is math.)
Jordan Mason under 31.5 rushing yards (love this one)
David Sills under 24.5 receiving yards
Rashaad White under 18 rushing yards (disgusting, yet viable)

Overs with Life:

Jaleel McLaughlin over 18.5 rushing yards
- Still getting sprinkled-in touches even with RJ Harvey.

🧾 THE MAYO OFFICIAL PROP OF THE SHOW

Using the Underdog Pick’em tool live:

David Sills — LOWER than 24.5 receiving yards
Jordan Mason — LOWER than 30.5 rushing yards

I put $100 on it → pays $350

Win that slip? You’ve basically paid for Sharpstack for the entire year

WEEK 13 DRAFTKINGS

Welcome back to the Week 13 DraftKings rundown, where ownership projections swing harder than my mood when Home Depot doesn’t have enough staff to unlock the paint aisle.

This week’s content around the industry is thin, so anyone using optimizers is basically pulling from the same pool. Luckily, 4for4 has the goods, Squirrel Patrol/ John Breslin have full builds coming, and if you want the optimizer I use:
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That’s basically five bucks for the rest of the year. Even if you’re just playing the dime-time, this is the cheapest way to learn how to actually build lineups.

🏃‍♂️ Running Back Ownership & Values

Highest Owned RBs (early reads):

De’Von Achane – ~40%
Breece Hall – ~30%
Kamani Vidal – ~21% (no Hampton)
Kenneth Walker – 20%
Bijan Robinson – 18%

Walker at 20%? Hate it. It’s a spot you need to guess right, and Charbonnet can nuke the workload at any moment.

Bijan is the better pure play, but cold weather + touchdown variance could easily flip the script to Tyler Allgeier stealing early work.

RBs I Actually Like

• Achane & Hall – Best values on the slate. Salary is broken.
• Bijan – Still a great GPP play if touchdowns fall correctly.
• Kyren Williams (13%) – Underrated leverage.
• Quinshon Judkins – Bad run D matchup, 20+ touches, goal-line wildcat.
• James Cook (10%) – Steelers give up the most plays per game. Cook is being ignored.
• Devin Neal ($5,000) – My favourite deep value. Full workload, cheap, gets you up to McBride or premium WRs.

RBs I’m Fading

Jonathan Taylor ($9,800) & McCaffrey ($9,700) – Salary is insane this week.
Tony Pollard – Just don’t.

Lowest I’d go?
Devin Neal at $5,000. Anything below that is meme-building. (Unless Bam Knight is OUT last second and Michael Carter slips in to all the work)

📊 Cash Build Snapshot

One of the top projections this week:

Herbert
Hall
Achane
Waddle
Nico Collins
Chris Olave
Titans DST

Not correlated, but high raw projection. If you’re tweaking:

Adjust ownership caps
Blend ceilings
Loosen/tighten randomness
Everything is customizable.

👐 Wide Receivers

Most Owned:
JSN → Puka → Waddle → Nico → Tet McMillan → Olave
All “fine,” but heavily duplicated in optimizers.

Best GPP Values

Alec Pierce – $4,800
Jaylen Waddle
Tet McMillan
Nico Collins
Puka Nacua
Chris Olave

Best Cheap WRs

John Metchie III – $3,800
Jayden Higgins – $3,900
Both project extremely well sub-$4K.

If You Want to Go Full Galaxy Brain

AD Mitchell + John Metchie + Tyrod Taylor let’s you jam in multiple JSN/Puka/McBride/Taylor level players if you’re deranged enough.

🧵 Tight End

Let’s be honest:
We all assume it’s Trey McBride slate every slate.

This week?
He’s only 6% but expensive.

Top TE Values

Orande Gadsden II – 18%
Brock Bowers – $5,800
Colby Parkinson – volatile but projects well
Dalton Schultz
McBride (leverage play!)

If McBride is really this low-owned? Pay the tax. He’s been smashing too consistently.

🧠 Quarterback

Highest Owned:

Herbert
C.J. Stroud ($5,000!)
Tyrod Taylor ($4,300)
Josh Allen
Darnold / Stafford

QB Values Ranked

Herbert
Tyrod
Stroud
Tua
Trevor Lawrence
Allen

Tua stacks rate out great:
Tua + Achane + Waddle + Neal runback = cheap, strong, unique.

Stroud stacks → expect Stroud + Higgins + Pierce to be extremely common.

🛡️ Defense