2026 Week 6 NFL Weekend Cheatsheet: Injuries, Picks, DFS, Prop Parlay, Fantasy Rankings

Oct 18, 2026

IMAGN IMAGES via Reuters Connect

WEEK 6 NFL WEEKEND CHEATSHEET

Pat Mayo has the ultimate NFL Week 6 Cheat Sheet. Get the latest on key player injuries, updated fantasy football rankings, DFS ownership strategies, and top Underdog Fantasy props for Week 6. Plus, Alex Blickle stops by to talk DFS leverage and underdog plays, and fill out another Underdog entry to try and give away $500. Then, Adam Pranica and Mayo make their Week 6 NFL spread picks for the Circa Millions contest.

NFL Week 6 Cheatsheet + $500 Giveaway & Best Prop Bets

Week 6 RB Injuries

David Montgomery (groin) — OUT
Breece Hall (quad) — OUT
Zach Charbonnet (knee) — OUT
Kyle Monangai (thumb) — OUT
Saquon Barkley (hamstring) — OUT
Dylan Sampson (knee) — OUT
Jeremiyah Love (ankle) — OUT
Jacory Croskey-Merritt (groin) — Expected OUT
Ashton Jeanty (ankle, foot) — Leaning IN
Alvin Kamara (back) — Leaning IN
Rico Dowdle (toe) — Expected IN
Tyjae Spears — Questionable
TreVeyon Henderson (ankle) — Questionable
Quinshon Judkins (ankle) — Questionable
Chris Brooks (ankle) — Questionable
Raheim Sanders (hip) — PLACED ON IR
Will Shipley (leg) — PLACED ON IR

FULL UPDATED WEEK 6 RANKINGS BY POSITION

Week 6 WR Injuries

Deebo Samuel (hamstring) — Expected OUT
Tre' Harris (hamstring) — OUT
Rashee Rice (hamstring) — OUT
Adonai Mitchell (finger) — OUT
Marvin Harrison Jr. (Traded) — Expected IN
Jalen Nailor (concussion) — Expected IN
Ja'Kobi Lane (wrist) — Expected IN
A.J. Brown (ankle) — Expected IN
Jalen Coker (quad) — Expected IN
KC Concepcion (concussion) — Expected IN
Quentin Johnston (chest) — Expected IN
Omar Cooper Jr. (ankle) — Expected IN
Ladd McConkey (foot) — Expected IN
Denzel Boston (foot) — Questionable
Stefon Diggs (hamstring) — Questionable
Joshua Palmer (shoulder) — Questionable
D.J. Moore (shoulder) — Questionable
Mike Evans (ribs/Achilles) — Questionable
Caleb Douglas (ankle) — ON BYE
Pat Bryant (ankle) — PLACED ON IR
Mack Hollins (calf) — PLACED ON IR
Michael Pittman (foot) — PLACED ON IR
Roman Wilson (finger) — PLACED ON IR

Week 6 TE Injuries

Kenyon Sadiq (concussion) — Leaning IN
Tyler Warren (groin) — Questionable
Pat Freiermuth (calf) — Questionable
T.J. Hockenson (concussion) — ON BYE

Week 6 QB Injuries

Michael Penix (ribs) — IN
Caleb Williams (hamstring) — IN
Lamar Jackson (ankle) — OUT
Baker Mayfield (thumb) — OUT
Jalen Hurts (calf) — PLACED ON IR

NFL Week 6 Props + $1000 GIVEAWAY

Blickle came on the Saturday Update show and helped collab on a +8490 Underdog entry. If it wins, I’m giving ONE LUCKY PERSON $500!!!!

BLICKLE’S FAV PROPS

Carnell Tate (Higher than 19.5 Longest Reception): Blickle is back on Tate again. Tate ranks near the top of the NFL in weighted opportunity rating and team air yards share. He's constantly running downfield routes and getting open, he just needs his QB to hit him while open this week.

Michael Penix Jr. (Higher than 239.5 Passing + Rushing Yards): A phenomenal number that blends a safe passing floor with rushing upside as a bonus.

Rome Odunze (Higher than 39.5 Receiving Yards): Odunze has hit this number in every single game this season, spanning 3 QBs, showing increasing target integration in a game with a high implied total.

MAYO’S FAV PROPS

Alvin Kamara (Lower than 8.5 Longest Rush): And I’m picking on Kamara again. AL-VINNNNNNN continues to lack explosive upside on the ground. This is obvious. This week, he’s dealing with a back injury combined with a split backfield. Now we hope a defender doesn’t fall down.

Kyren Williams (Lower than 19.5 Receiving Yards): Inflated recent lines make this under a play if the Rams actually do what they’re expected to do. In negative or highly competitive game scripts, Kyren's receiving volume spikes, but a positive game flow against Arizona points to a lighter workload through the air.

Daniel Jones (Lower than 5.5 Longest Rush): Another one of my staple of weekly Unders. Jones is a shell of his former mobile self, and the Colts offense wants to keep him out of harm's way.

PLAY THE PME BOOSTED PARLAY AT COOLBET RIGHT NOW!!!!

LAST ONE

Tony Pollard (Higher than 12.5 First Quarter Rushing Yards): Facing a porous Colts run defense, the Titans want to establish the ground game early before game script potentially gets away from them.

Turn on Notifications, drop a comment with your FAV prop of the week, and if Pat's 7-pick Underdog slip hits, someone with a winning prop play in the comment section gets $500!

TAIL OR FADE + code “MAYO” at underdog for a deposit bonus up to $1000

Week 6 Best Bets

Pat Mayo, George Tsilfidis, and Cam Stewart break down the biggest NFL matchups for Week 6, share their official Gold, Silver, and Bronze picks, and dive into the week’s sharpest betting angles and spreads.

NFL Week 6 Best Bets, Teasers, Props, Cam vs AI

GOLD

MAYO: JAX -2.5
G-STACK: NYG/NO o45.5
CAM: NO -1

SILVER

MAYO: PIT -2.5
G-STACK: NE -7
CAM: DAL +1.5

BRONZE

MAYO: LV +5.5
G-STACK: TEN +7
CAM: LV -5.5

6-POINT GROUP TEASER: KC -2/NE -1/PHI +10.5
SEASON TEASER RECORD: 1-4

Week 6 Spread Picks

Pat Mayo, Geoff Fienberg and Tim Anderson make their Week 6 NFL picks, against-the-spread game previews, super locks, and free money teasers. Get all your betting strategy, injury breakdowns, and team analysis sorted for every matchup on the slate. Plus, a Mini Cust Corner on Fast Food GLP-1 Menus, Golf Cart Lanes, gym etiquette, and yachting

NFL WEEK 6 PICKS CHEATSHEET

MAYO: SEA -3, JAX -2.5, CHI -3, CLE +4.5, TEN +7, NYJ +7, NYG +1, CAR +1, PIT -2.5, ARZ +13, KC -8.5, LV +5.5, DAL +1, SF -7.5

GEOFF: SEA -3, JAX -2.5, CHI -3, CLE +4.5, TEN +7, NYJ +7, NO -1, CAR +1, TB +2.5, LAR -13, KC -8.5, LV +5.5, DAL +1, SF -7.5

CUST: DEN +3, JAX -2.5, ATL +3, BAL -4.5, IND -7, NYJ +7, NO -1, CAR +1, TB +2.5, ARZ +13, LAC +8.5, LV +5.5, GB -1, SF -7.5

THE COIN: DEN +3, HOU +2.5, ATL +3, CLE +4.5, TEN +7, NE -7, NYG +1, PHI -1, PIT -2.5, ARZ +13, KC -8.5, LV +5.5, GB -1, WAS +7.5

2026 RECORD

MAYO: 9-5 (39-37)
GEOFF: 7-7 (36-40)
CUST: 6-8 (36-40)
COIN: 5-9 (30-46)

SUPERLOCK

MAYO: JAX -2.5 (2-3)
GEOFF: CAR +1 (2-3)
CUST: IND -7 (3-2)

SURVIVOR PICK

MAYO: OUT (BAL, KC, SF, JAX, DAL OUTTTT!)
GEOFF: OUT (TB OUTTTTT!!!! LAC OUTTT!!!!)
CUST: OUT (TB OUT!!!!!!! LAC OUTTT!!!!)

CUST “FREE MONEY” PICKS

6-POINT TEASER: IND -1/CAR +7/TB +8.5/SF -1.5

Cust’s 2026 Record: 2-3
Cust’s Lifetime Record: 34–169

Week 6 DraftKings Values & Ownership

Pat Mayo and Tambo and Tambo from Ship It Nation break down the Week 6 DraftKings slate, looking at optimal builds, high-value running backs, game stacks, and leverage plays. From navigating key injuries (like high ankle sprains and game-time decisions) to finding the best mid-tier wide receiver value and building winning tournament lineups, we cover everything you need to crush your DFS contests this week.