Week 2 NFL Weekend Cheatsheet: Injuries, Picks, DFS, Props, Updated Fantasy Football Rankings

Sep 19, 2026

IMAGN IMAGES via Reuters Connect

Pat Mayo provides the latest on key player injuries, updated fantasy football rankings, DFS ownership strategies, and top Underdog Fantasy props for Week 2. Plus, Alex Blickle stops by to talk Props, DFS leverage, and Underdog plays. Then, Adam Pranica joins Pat to break down their Circa Millions contest picks.

NFL Week 2 Cheat Sheet: UPDATED Injuries, Rankings, Props, DraftKings & Spread Picks

WEEK 2 NFL INJURIES

RB

TreVeyon Henderson — IN
Alvin Kamara (knee) — IN
Kaelon Black (groin) — Likely IN
Sean Tucker (hamstring) — Expected IN
RJ Harvey (hamstring) — Questionable
Ty Johnson (hamstring) — Missed Week 2
Jordan Mason (thumb) — Placed on IR

FULL WEEK 2 RANKINGS BY POSITION

WR

Nico Collins (hamstring) — OUT
Marvin Mims (foot) — OUT
Jauan Jennings (personal) — OUT
Michael Pittman Jr. (foot) — OUT
Zay Flowers (hamstring) — OUT
Puka Nacua (hip) — Questionable (Plays Monday night, so move to your FLEX position to give yourself more options should be deemed inactive on Monday afternoon: RAMS TEs, Malachi Fields, Devin Singeltary, maybe Tutu Atwell)
Ladd McConkey (ribs) — Questionable
Chris Olave (hamstring) — Leaning IN (Olave travelled to Baltimore yet WR Kevin Austin elevated to main rosted by Saints as well.)
Jordan Whittington (quad) — Questionable
Jalen McMillan (knee) — Questionable
Tory Horton (hamstring) — IN
Ja'Kobi Lane (wrist) — OUT multiple weeks
Omar Cooper Jr. (ankle) — Placed on IR
D.J. Moore (Shoulder) — OUT 1-3 Weeks

QB

Joe Burrow (back) — IN
Tua Tagovailoa (oblique) — OUT; Cooper Rush Starting
Kyler Murray (concussion) — OUT; Carson Wentz Starting
Sam Darnold (Hip) — OUT Multiple Weeks

TE

Chigoziem Okonkwo (hamstring) — OUT
Brock Bowers (Ankle) — Expected OUT

NFL Week 2 Props

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MAYO’S PICKS

Raheim Sanders — o1.5 Receptions: Sideshow Raheem is running pass-catching routes out of the backfield with Dylan Sampson out. If the Browns stink and go into catch-up mode, he’s going to clear this easily.
Jaylin Noel — o25.5 Receiving Yards: With Nico Collins out for Houston, Noel is stepping into a increase in target share.
Mack Hollins — o35.5 Receiving Yards: The Steelers run a ton of zone coverage, and Hollins completely obliterates zone. He’s a trusted first-look option when Drake Maye is under pressure with AJ Brown out, and he can clear this on a single catch.

Other Mayo Props: Drake London & Jerry Jeudy under yards; Christian Watson longest reception; Cooper Rush under 1.5 Rushing Yards

BLICKLE’S PICKS

Mike Evans — o8.65 Fantasy Points (Half-PPR): Blickle calls this one of his favorite NFL props since the start of last season. Evans is clearly prioritized in a Kyle Shanahan offense designed to get him one-on-one operating space. At this low number, a single touchdown basically gets him there, making it an incredible value since there are outs even if he doesn’t score.
Bucky Irving — o11.95 Fantasy Points (Half-PPR): Despite Sean Tucker returning to the mix, Bucky looked explosive in Week 1, reminiscent of his rookie year. He’s heavily involved in both the running game and the passing attack, and his role is secure.
Jordan Addison — o6.7 Fantasy Points (Half-PPR): With Jauan Jennings out for personal reasons, Addison’s path to targets clears up. He has a history of high-ceiling games with Carson Wentz, and this correlates nicely with the game script if Minnesota is playing from behind.
Cam Ward — u33.5 Longest Completion: Backed by an Eagles defense that led the league in preventing wide-open targets and forcing tight coverage last year, Ward won’t have the time to hold the ball and heave it downfield against a fierce pass rush.

Aaron Jones — o15.5 Receiving Yards: Jordan Mason is on IR, locking Jones into a massive 70%+ share of the backfield against a bad Bears defense. If they get down, he’ll pile these up through the air in a hurry. Even in a neutral script, expect Wentz to live off Jones dumpoffs.

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Raheim Sanders o1.5 Catches
Mack Hollins o35.5 REC Yards
Jaylin Noel o25.5 REC Yards

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Week 2 Best Bets

Pat Mayo, Rob Pizzola, and Cam Stewart break down their official Gold, Silver, and Bronze best bets for NFL Week 2, battle it out against AI, lock in their parlay teasers, and dive into the usual chaos (remodel disasters, fridge mysteries, and shoe troubles).

NFL Week 2 Best Bets, Teasers, Props, Cam vs AI

GOLD

MAYO: TB -8
PIZZOLA: NYJ +3.5
CAM: HOU -2.5

SILVER

MAYO: PHI -7
PIZZOLA: DAL -3.5
CAM: TEN +7

BRONZE

MAYO: ATL +2.5
PIZZOLA: ARZ +4
CAM: IND +7

6-POINT GROUP TEASER: TB -2/LAC -0.5/JAX +8.5

SEASON TEASER RECORD: 0-1

Week 2 Spread Picks

Pat Mayo, Geoff Fienberg and Tim Anderson make their Week 2 NFL picks, against-the-spread game previews, super locks, and free money teasers. Get all your betting strategy, injury breakdowns, and team analysis sorted for every matchup on the slate. Plus, a Mini Cust Corner on NFL Highlights & Putter Cover Complaints, Fantasy Draft Etiquette & Office Potlucks, Cable Box Business Idea Discussion, BBQ Restaurant No-Tip Culture, Heely Shoes & Golf Course Stories

Week 2 DraftKings Values & Ownership

Pat Mayo and Tambo from Ship It Nation break down everything you need to know for Week 2 DraftKings DFS. From managing high-ownership chalk like Bijan Robinson and Aaron Jones to finding contrarian game stacks, weather spots, and tournament-winning leverage, they cover all the optimal roster constructions for the upcoming slate. Plus, get the latest updates on key injuries and early value plays. Plus, get all the best value plays, tight end pivots, and lineup builds utilizing 4For4 tools. (“Mayo50” will get you 50% OFF all DFS Tools as well. There is no limit to the people who want to get that deal.)

WATCH: Week 2 DraftKings Picks | Strategy, Ownership Breakdown, & Lineup Building

RBs Projected Ownership 15%+

WR Projected Ownership 18%+

TE Projected Ownership 10%+

QB Projected Ownership 10%+

DST Projected Ownership 8%+

Tampa Bay Buccaneers
Baltimore Ravens

CHEAP DK WRS

Mack Hollins ($4,300) & Devaughn Vele ($4,200): Brought up as viable cheap salary-savers to fit in expensive stacks.
Jaylin Noel ($3,700): A great punt option stepping into a massive target share boost with Nico Collins out.
Caleb Douglas ($3,700): Positioned well for garbage-time volume or catch-up mode against San Francisco.
Ted Hurst III ($3,200): Excellent value if Jalen McMillan is ultimately forced to sit. Terrible play if McMillan plays

ELITE PIVOT DST

Eagles DST: Blickle’s preferred elite defense of the week. Highly recommended to pay up for them against Tennessee to capture a high ceiling against a mistake-prone offense. I like TB, but he made some pretty compelling cases for PHI. Primarily, that they’re expected to be half the ownership.

WEEK 2 SUNDAY NIGHT LIVE

Cust and I are going LIVE at 715pm ET on MMN Sunday for the INSTANT OVERREACTIONS along with PPR TYLER!!!!! As a young, Tyler has a chance to become the new PME Youth Correspondent. I’m sure Cust will ask him who was the 3rd lead in Hogan’s Heroes and lose his mind if Tyler doesn’t know. It’ll be good times!

We’ll be recapping the games, taking some cases for Judge Cust, and guessing the spreads for Week 2, along with props for SNF. It’s easily the most fun way to kill the time before SNF starts. Come hang and get in the chat. Oh, and NEXT WEEK Kenny Kim will be on the show, and after PME LIVE we’ll be doing a LIVE members call-in CUST CORNER. If you ever wanted to talk to Cust LIVE ON AIR, I suggest becoming a YouTube member. That show will be released later for everyone too.