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It has been a frustrating year for Goodwin and his owners. The frustration may continue if he can't play in a cherry Week 3 matchup against a beleaguered Chiefs pass defense. Should the speedster see the field, he is a WR3 with a massive ceiling. The current total for the game sits at 55 points, which is the largest number of any game this week. A shootout is in order, so even if Goodwin doesn't suit up, there is value to be had among 49ers pass-catchers. Pierre Garcon would see a solid bump, perhaps to low-end WR2 status. Tight end George Kittle, already a top-10 option this week, would likely benefit from a higher target floor. Beyond those two, it gets sketchy, with Goodwin's backup Dante Pettis the most likely beneficiary. He has done little in Goodwin's stead thus far, but there would be worse WR4/WR5 dart throws this week.

Marlon Mack being ruled out is probably for the better, as he hasn't been right for a while. This once again puts Jordan Wilkins in the driver's seat in the Colts' backfield. Up to this point that hasn't necessarily equaled fantasy usefulness, a problem that will likely be compounded in a tough matchup with the Eagles. Wilkins checks in as a low-end RB3 and backfield-mate Nyheim Hines an uninspiring RB4. Both players have limited ceilings.

Unable to practice all week, it's not a big surprise Doyle won't answer the bell. This puts Eric Ebron into a great position to help his owners. From Director of Forecasting John Paulsen: "Since 2016, tight ends have accounted for 28.8% of Andrew Luck’s completions, 28.2% of his passing yards and 40.0% of his touchdowns." Ebron is a top-five option for Week 3.

Jay Ajayi injured his back early Week 2 but was able to return, giving hope he'd be good to go this weekend. With that no longer the case, Corey Clement will get the call early and often against one of the worst run defenses in the league (Colts). We have him projected for nearly 20 touches and a fringe RB1 finish. Darren Sproles is also out, giving Clement a clear path to touches in the passing game as well. Wendell Smallwood is a desperation play as an RB3 with a reasonable floor but a low ceiling.

With the Vikings facing one of the worst teams in the league this week, Dalvin Cook being ruled out is a huge blow for his fantasy owners. Those savvy enough to grab Latavius Murray off the waiver wire will reap the rewards, as Minnesota should enjoy a positive game script for nearly all 60-minutes, setting him up for a massive workload. Murray was involved in the passing game during his time in Oakland, but the Vikings haven't used him in that capacity thus far. Now that Jerrick McKinnon is in San Francisco, that very well could change on Sunday. Mike Boone likely serves as Murray's backup and could see a good amount of work if the game gets out of hand.

This may be a first for news updates here on 4for4, but it is something to monitor if you planned to start Hyde tonight. As of now, the report is that he will play, but that could change at any time. If he doesn't go, Nick Chubb suddenly becomes an interesting dart throw as an RB2 with upside if the game script brings him 15+ touches.

Ajayi went out on his first touch but managed to return in the second half last week. That makes his absence a bit of a surprise development. Corey Clement should be snapped up off the waiver wire in case Ajayi can't suit up this weekend. He would be a workload-based RB2.

We don't know much about Doyle's status other than that he hasn't been able to practice. In the event he sits, Eric Ebron would be in the TE1 discussion.