Isaac Guerendo Fantasy Football Profile, News and Stats

Isaac Guerendo
RB
, San Francisco 49ers

Age: 25
Weight: 221 lbs
Height: 6' 0"
College: Louisville

ADP: 197
Depth Chart Ranking: 3

Pts	RuYds	RuTD	Rec	RecYds
0	0	0	0	0

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Latest news

49ers RB Christian McCaffrey (calf) limited in Thursday's practice

Adam Schefter

Sep 04 · 8:10 PM EDT

49ers are listing RB Christian McCaffrey as limited at today’s practice due to a calf issue.

Related Players: Brian Robinson, Isaac Guerendo

Fantasy Impact:

It feels like we should panic, but players are limited in practice all the time (right?). We'll keep an eye on things but Robinson should be in our queues to plug in as an RB2 in case CMC is sidelined.

Scouting report

by Bill Riccette

· Dec 06, 2024 · 12:48 PM EST

SF RB Isaac Guerendo - Week 14 Fantasy Football Outlook

Week 14 vs. Chicago Bears

It's now Isaac Guerendo's backfield in San Francisco after both Christian McCaffrey and Jordan Mason were injured in Buffalo last week. Guerendo has averaged 4.7 yards per carry this season and does have a 99-yard outing back in Week 6 against the Seahawks. Guerendo is certainly worth looking at this week in a favorable matchup against the Bears, who rank 25th against the run and are allowing almost five yards per carry. Guerendo has RB2 upside this week.

2025 Strength of Schedule - SF

W1	W2	W3	W4	W5	W6	W7	W8	W9	W10	W11	W12	W13	W14	W15	W16	W17	W18
12 @SEA	15 @NO	17 ARI	10 JAX	1 @LAR	21 @TB	27 ATL	9 @HOU	31 @NYG	1 LAR	17 @ARI	16 CAR	2 @CLE	BYE	30 TEN	14 @IND	25 CHI	12 SEA

Schedule difficulty based on schedule-adjusted, positional defensive ranking. Top DEF = 1, bottom DEF = 32.

Game Stats


Week	Opp	RuAtt	YPC	Rec	YPR	STD	0.5 PPR	PPR	Snaps	%
1	@SEA	0	0.00	0	0.00	0.0	-	0.0	0/76	0.0%
2	@NO	0	0.00	0	0.00	0.0	-	0.0	0/71	0.0%
3	ARI	0	0.00	0	0.00	0.0	-	0.0	0/65	0.0%
4	JAX	0	0.00	0	0.00	0.0	-	0.0	0/66	0.0%
5	@LAR	0	0.00	0	0.00	0.0	-	0.0	0/86	0.0%
6	@TB	0	0.00	0	0.00	0.0	-	0.0	0/69	0.0%
7	ATL	0	0.00	0	0.00	0.0	-	0.0	0/67	0.0%
8	@HOU	0	0.00	0	0.00	0.0	-	0.0	0/48	0.0%
9	@NYG	0	0.00	0	0.00	0.0	-	0.0	0/66	0.0%
10	LAR	0	0.00	0	0.00	0.0	-	0.0	0/63	0.0%
Per game			0	0.00	0	0.00	0.00	0	0	0.00/0.00	0.00%
Totals			0	0.00	0	0.00	0	0	0	0/677	0.00%

Previous Games vs. ARI


Season	Week	Opp	RuAtt	RuYds	RuTD	Fum	YPC	Rec	RecYds	RecTD	Tgts	STD	0.5 PPR	PPR	Snaps	%
2025	3	ARI	0	0	0	0	0.00	0	0	0	0	0.0	-	0.0	0/65	0.00%
2024	18	@ARI	2	5	0	0	2.50	0	0	0	0	0.5	0.50	0.5	4/76	5.26%
2024	5	ARI	5	22	0	0	4.40	0	0	0	0	2.2	2.20	2.2	9/64	14.06%
Average					2.33	9.00	0.00	0.00	2.30	0.00	0.00	0.00	0.00	0.90	0.90	0.90	4.33/68.33	6.44%

Isaac Guerendo