Isaac Guerendo Fantasy Football Profile, News and Stats

Isaac Guerendo
RB
, San Francisco 49ers

Age: 26
Weight: 221 lbs
Height: 6' 0"
College: Louisville

ADP: 197
Depth Chart Ranking: 3

Pts	RuYds	RuTD	Rec	RecYds
0	0	0	0	0

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Latest news

49ers RB Christian McCaffrey (calf) limited in Thursday's practice

Adam Schefter

Sep 04, 2025 · 8:10 PM EDT

49ers are listing RB Christian McCaffrey as limited at today’s practice due to a calf issue.

Related Players: Brian Robinson, Isaac Guerendo

Fantasy Impact:

It feels like we should panic, but players are limited in practice all the time (right?). We'll keep an eye on things but Robinson should be in our queues to plug in as an RB2 in case CMC is sidelined.

2026 Strength of Schedule - SF

W1	W2	W3	W4	W5	W6	W7	W8	W9	W10	W11	W12	W13	W14	W15	W16	W17	W18

Schedule difficulty based on schedule-adjusted, positional defensive ranking. Top DEF = 1, bottom DEF = 32.

Game Stats


Week	Opp	RuAtt	RuYds	RuTD	Fum	YPC	Rec	RecYds	RecTD	Tgts	YPR	STD	0.5 PPR	PPR	Snaps	%
1	@SEA	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/76	0.0%
2	@NO	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/71	0.0%
3	ARI	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/65	0.0%
4	JAX	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/66	0.0%
5	@LAR	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/86	0.0%
6	@TB	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/69	0.0%
7	ATL	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/67	0.0%
8	@HOU	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/48	0.0%
9	@NYG	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/66	0.0%
10	LAR	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/63	0.0%
11	@ARI	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/55	0.0%
12	CAR	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/70	0.0%
13	@CLE	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/67	0.0%
14	BYE	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
15	TEN	0	0	0	0	0.00	0	0	0	0	0.00	0.0	-	0.0	0/74	0.0%
O Injury Details (w16) Status: Out Injury: Gameday Inactive 16	@IND	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
17	CHI	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
O Injury Details (w18) Status: Out Injury: Gameday Inactive 18	SEA	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Per game			0	0	0	0	0.00	0	0	0	0	0.00	0.00	0	0	0.00/0.00	0.00%
Totals			0	0	0	0	0.00	0	0	0	0	0.00	0	0	0	0/943	0.00%

Isaac Guerendo

Latest news

49ers RB Christian McCaffrey (calf) limited in Thursday's practice

2026 Strength of Schedule - SF

Game Stats

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