Team news: Arizona Cardinals

Cardinals are not optimistic that WR Larry Fitzgerald, listed as questionable with a groin injury, will be able to play vs the Rams, per source. With Christian Kirk out, Fitzgerald could try to surprise Arizona. But the team was not counting on having him available.

Fire up DeAndre Hopkins this week, as he could see a lot of targets if the Rams make this a game. KeeSean Johnson and Andy Isabella will likely start, but Arizona doesn't seem to like to use either one enough for fantasy purposes.

Cardinals placed WR Christian Kirk on the Reserve/COVID-19 list.

The Cardinals will be without Christian Kirk for a win-or-go-home contest in Week 17 against the Rams. Second-year wideouts Andy Isabella and KeeSean Johnson should see a bump in usage, with Larry Fitzgerald still a game-time decision.

Cardinals RB Chase Edmonds is questionable for Week 17 against the Los Angeles Rams, according to Lindsey Thiry of ESPN.

Edmonds did not practice all week, which is not a good sign. Kenyan Drake would be asked to carry the load without his running mate available.

Cardinals quarterback Kyler Murray practiced Wednesday and told reporters he will be "good" for Sunday's game against the Rams.

Murray left late in Week 16 after injuring his leg but all of the reports out of Arizona have suggested it is something he can play through, especially with the Cardinals fighting for their playoff lives in Week 17. The fact that Murray is practicing on Wednesday confirm those suggestions and we should expect Murray under center against the shorthanded Rams come Sunday.

HC Kliff Kingsbury is "hopeful" QB Kyler Murray (leg) will play against the Rams.

Murray's status will need to be monitored this week it sounds like, and hopefully owners will have a better feel for things on Wednesday. The Cards are going up against a banged up Rams team in Week 17. According to the tweet, Kinsburgy said Murray is capable of playing with limited mobility: "If he has to adjust his style, he can definitely play from the pocket."

Cardinals QB Kyler Murray limped off the field with an apparent lower-leg injury at the end of Saturday’s loss to the 49ers.

Murray took a crushing hit at the end of the game and limped off the field and to the locker room. Murray had a rough night even before the injury, including throwing a killer interception in a 20-12 loss that dealt a major blow to the Cardinals’ playoff hopes. They no longer control their destiny to make the playoffs. We’ll get more word on Murray, but he’ll probably try to tough it out in what is now an absolute must-win in Week 17 against the Rams.