For a second straight day, 49ers’ WR Deebo Samuel was a full participant at practice and is on track to play Sunday at Jacksonville.

Related Players: Brandon Aiyuk, Ray-Ray McCloud, George Kittle

Looks like the bye week did Samuel some good, and if he's a full participant already, we should expect his normal workload upon his return. He has 397 yards and two all-purpose touchdowns through six games this season, and should be boosted back into WR2 consideration this week.

For the Sunday night game, Cowboys standout defender Micah Parson (knee) and 49ers standout offensive weapon Deebo Samuel (knee) will both be at less than 100%.

Related Players: Brandon Aiyuk, George Kittle, Ronnie Bell

As Ian mentions in the video, Samuel did play in Week 4, although it was in an extremely limited role as they sprinkled in a couple of carries. Rapoport expects more for Week 5 but cautions that the team will be careful with his knee injury.

Only two 49ers I did not see participating during early open portion of Thursday’s practice: WRs Deebo Samuel and Jauan Jennings. Jennings was doing some work on the side. WR Brandon Aiyuk is out of blue no contact jersey. LB Dre Greenlaw also back in the mix.

Related Players: Ronnie Bell, Ray-Ray McCloud

In addition to Bell and McCloud, Tay Martin, Chris Conley and Isaiah Winstead are options the team could pull from their practice squad. We'll keep an eye on all of these injuries heading into Friday's practice, but we could be looking at a very run-heavy approach from the 49ers as 14-point favorites on Sunday.

49ers Monday practice vibes Week 4: Brandon Aiyuk is participating but not seen [is] Deebo Samuel (ribs).

Samuel did return to the game in Week 3 so that's at least some good news for owners monitoring his rib injury. Aiyuk missed Week 3 so it seems like he's trending in the right direction. We'll know more about both players as the week goes on. The Niners host the Cardinals in a later afternoon game in Week 4.

49ers’ WR Brandon Aiyuk, listed as questionable for tonight’s game due to a shoulder injury, is not expected to play vs. the Giants.

Related Players: Deebo Samuel, Jauan Jennings, Ronnie Bell

The 49ers rarely have their "Big Four" all on the field simultaneously, which is a shame because it's such a fun offense to watch when it's rolling. We can expect a slight uptick in target share for both George Kittle and Deebo Samuel, while it's also likely Christian McCaffrey will get a little more action as a receiver. Though Jauan Jennings had a couple of big plays in the team's Week 2 victory, it's not enough to consider him in fantasy outside of DFS Showdown slates.

Brandon Aiyuk (shoulder) will be, as expected, a game-time decision for 49ers-Giants on TNF, per John Lynch on KNBR

Related Players: Deebo Samuel, Jauan Jennings, Ronnie Bell

The 49ers rarely have their "Big Four" all on the field simultaneously, which is a shame because it's such a fun offense to watch when it's rolling. We can expect a slight uptick in target share for both George Kittle and Deebo Samuel, while it's also likely Christian McCaffrey will get a little more action as a receiver. Though Jauan Jennings had a couple of big plays in the team's Week 2 victory, it's not enough to consider him in fantasy outside of DFS Showdown slates.

According to source, Brandon Aiyuk had a CT scan yesterday. It revealed no break to the clavicle area.

Those in the medical field believe Aiyuk is dealing with an AC sprain. And as the post said, his status for Thursday night's game will be all about pain tolerance. It all makes Aiyuk a potential risky fantasy play even if he's active for TNF. Continue to monitor his progress.

When asked whether there are any potential long-term concerns surrounding Brandon Aiyuk, Kyle Shanahan said, “I wouldn’t think so. I mean, I know he was hurting a little bit, but he was able to play through it. So I think he’ll be alright.”

Aiyuk was listed as DNP for Monday. The 49ers have a short week in a home game against the Giants, so the team could use some caution with a quick turnaround and not rush him back. We'll continue to monitor his progress as we get closer to TNF.

In the middle of a busy Monday as the 49ers prepare to face the New York Giants on a short week, the team was uncertain about the status of wide receiver Brandon Aiyuk.

Aiyuk sustained a left shoulder injury during the opening drive of the 49ers’ Week 2 victory over the Los Angeles Rams.

He made a diving 13-yard reception and landed hard on the artificial surface at SoFi Stadium.

“It’s too early to have all the answers to the injuries, yet,” Shanahan told local reporters on a conference call.

Aiyuk’s availability appears to be the 49ers’ biggest injury concern entering the Week 3 game. The story added Aiyuk played 30 of the 49ers’ 57 offensive plays, as the 49ers mixed in rookie wide receiver Ronnie Bell and Jauan Jennings, each of whom was on the field for 27 snaps. Aiyuk owners will likely want to come up with a backup plan now since it's a short week for the Niners.

GM John Lynch announced the 49ers have exercised the 2024 fifth-year option for receiver Brandon Aiyuk, valued at $14.1 million, but declined the option for defensive tackle Javon Kinlaw. The 49ers had previously hinted that they’d make both of these moves, which are obviously tethered to the fact that Aiyuk has been productive — he notched a 1,000-yard season in 2022 — while Kinlaw has struggled to stay available due to knee issues.

Related Players: Danny Gray, Ray-Ray McCloud

The 49ers did add former Alabama tight end Cameron Latu, but we should expect them to add more talent to their pass-catching group before the draft is over. They have six late-round picks to do so, and whether or not any of those picks hit may effect the team's long-term view of Brandon Aiyuk.