49ers WR Brandon Aiyuk suffered season-ending knee injury

Oct 21, 2024

Sources: 49ers WR Brandon Aiyuk suffered a season-ending knee injury on Sunday, tests confirmed.

Fantasy Impact:

Anyone who held on to Jennings should be in good shape as he will likely slide in as the team's WR2 behind Deebo. Jennings didn't play in Week 7 because of a hip injury but the team is hoping to have in back for Week 8, according to reports. Pearsall was active for the first time and caught three balls for 21 yards. Cowing had two catches for 50 yards. Both rookies could be options behind Samuel, Kittle and likely Jennings, but may not be consistent fantasy producers. We reported McCaffrey is looking to return on Nov. 10 and it's possible he's counted on as a receiver more than a rusher once he's back.

today

49ers RB Isaac Guerendo "plans to play" TNF

Adam Schefter

2 hours ago

San Francisco 49ers running back Isaac Guerendo plans to play Thursday night against the Los Angeles Rams despite his sprained foot, sources told ESPN's Adam Schefter.

Guerendo, who is listed as questionable, insists he "feels good," sources said.

Fantasy Impact:

We're projecting Patrick Taylor as the next man up in the 49ers' version of running back roulette *if* Guerendo is forced out, as he easily has the most familiarity with the team. Abanikanda can be stashed if that's not the case, but shouldn't be in starting consideration if Guerendo does indeed miss Week 15.

Otherwise, consider the fourth-round rookie a fantasy RB2.

yesterday

49ers RB Isaac Guerendo listed as Questionable for TNF

Ian Rapoport

yesterday · 5:33 PM EST

— The 49ers ruled out LT Trent Williams (ankle) and S Malik Mustapha (chest), but RB Isaac Guerendo (foot) is questionable. So is Dre Greenlaw, who was full today.
— The Rams ruled out TE Tyler Higbee (knee) and Cobie Durant (chest).

Fantasy Impact:

We're projecting Patrick Taylor as the next man up in the 49ers' version of running back roulette, as he easily has the most familiarity with the team. Abanikanda can be stashed if that's not the case, but shouldn't be in starting consideration if Guerendo does indeed miss Week 15.

Rams WRs Demarcus Robinson, Jordan Whittington Questionable for TNF

Adam Schefter

yesterday · 5:30 PM EST

Rams are listing WR Demarcus Robinson (shoulder), WR Jordan Whittington (shoulder), and TE Davis Allen (shoulder) as questionable for Thursday night’s game versus the 49ers.

Related Players: Puka Nacua, Cooper Kupp, Tutu Atwell, Tyler Johnson

Fantasy Impact:

This doesn't really impact Nacua or Kupp either way, but Atwell could log a little extra work here. Consider him a very deep league WR5.