Jacob Cowing

49ers coach Kyle Shanahan told reporters that WR Deebo Samuel has a calf strain and will miss a few weeks. Another star injury for the Niners.

Related players: Brandon Aiyuk, Ricky Pearsall, Jauan Jennings, Ronnie Bell, Chris Conley, Jacob Cowing, George Kittle

It's a big blow to the Niners offense, which is already without Christian McCaffrey for an extended time. There was no mention on whether or not Deebo could end up on IR. Aiyuk should take over as the team's WR1, but who takes over as the WR2 is the bigger question. Kittle is likely next up after Aiyuk, which then leaves Jennings, Bell, Conley and Cowing at WR. Jennings is probably the leading candidate, but probably won't be a safe play in typical leagues. Cowing is a rookie who has stood out over the spring and summer and has been returning kicks, so it's possible he earns a bigger role with Deebo out.