The good news is that Kyle Shanahan expects wide receiver Brandon Aiyuk and the three other players on the reserve/COVID-19 list to be activated before the team leaves for its new home base in Arizona on Wednesday.
"My understanding is they'll all be off it today," Shanahan shared. "... My understanding is [Aiyuk] should be good to go, and all those guys (will be) totally normal for practice on Thursday (in Arizona)."
Aiyuk was had busted out before he went on the COVID list. He hasn't played since a 7-75-1 line on Nov. 15. His two games prior to that he posted lines of 8-91-1 and 6-115-0, and even scored a TD a week before that.