Head coach Kyle Shanahan said on Monday that third-round pick Tyrion Davis-Price is going to miss “a few weeks” after suffering a high-ankle sprain in Sunday’s win over the Seahawks.

Related players: Elijah Mitchell, Jeff Wilson, Kyle Juszczyk, Jordan Mason, Marlon Mack

The Niner RBs are falling fast as this comes after the team lost Mitchell for about 8 weeks, according to reports. With Wilson the lead back, Mason now becomes an injury away from possibly seeing a significant fantasy role. Juszczyk could continue to steal goal line TDs.

Jeff Wilson appeared in nine games last season after recovering from a torn meniscus in a knee. When he did play, he didn't look much like the player who led the team in rushing in 2020. Another year removed from that injury, Wilson appeared to be closer to his former self in training camp, though he managed just 22 yards on nine carries after replacing Mitchell at rain-soaked Soldier Field on Sunday.

"We've always been comfortable with Jeff, just because of his experience and what he has done here," Kyle Shanahan said. "We know what we're going to get."

Related players: Elijah Mitchell, Tyrion Davis-Price, Kyle Juszczyk, Jordan Mason, Marlon Mack, Deebo Samuel

What the Niners may not be comfortable with is what's behind Wilson at this point, though. Davis-Price is a rookie who was inactive in Week 1 behind undrafted rookie Mason. Mason played on special teams, however. The team signed Mack but he couldn't make the Texans roster. It's possible Samuel sees an uptick in rushes. The team seems like a Wilson injury away from a big problem at RB.

49ers are signing former Texans’ RB Marlon Mack to their practice squad, per source.

Related players: Jeff Wilson, Tyrion Davis-Price, Kyle Juszczyk, Jordan Mason

Wilson is expected to be the starter but Mack gives a little more security on the depth chart should he be needed as Davis-Price is a rookie.

The 49ers have waived RB Trey Sermon.

Related players: Elijah Mitchell, Jeff Wilson, Tyrion Davis-Price, Kyle Juszczyk

David Lombardi reports if Sermon clears waivers it's possible he'll be back. Following the 9ers RB situation probably made you dizzy this summer. Sermon, at one point, was called the clear RB2 by some who follow the team, but that's no longer is the case. Mitchell will be the lead back and after that a combination of Wilson and the rookie Davis-Price.

Shanahan didn’t rule out Elijah Mitchell for Thursday’s game against the Titans.

Related players: Jeff Wilson, Kyle Juszczyk, JaMycal Hasty

The story said Shanahan seemed skeptical about the running back’s prospects last week. Mitchell is now out of the concussion protocol but still is dealing with a knee injury suffered against the Seahawks on Dec. 5. Wilson played on 50 snaps last week with Hasty getting just three. It may be a battle to be ready on the short week for Mitchell, however.

Trey Sermon had two fewer snaps than he did against Green Bay, but it was clear he was more comfortable and that Shanahan and his assistants trusted him more. Still, the team hasn’t had a true third-down back after JaMycal Hasty went down with a high ankle sprain in Week 2.

For the second straight game, Kyle Juszczyk was the running back of choice on third downs or when the 49ers were in a hurry-up mode. Or the 49ers had a running back split out wide with no one in the backfield in those situations. The last two games have been heavier in three-receiver formations (56 percent of plays) than the first two (32 percent) when the 49ers had their full (or at least fuller) complement of tailbacks.

Related players: Elijah Mitchell

With Mitchell out with a shoulder injury, Sermon ran 19 times for 89 yards on the day. Meanwhile it was Juszczyk who was targeted four times and had four catches for 41 yards. Sermon was targeted once on the day. There will be some workload and role questions in this backfield when Mitchell is able to play again.

49ers RB JaMycal Hasty has a broken collarbone.

Related players: Jerick McKinnon, Kyle Juszczyk, Austin Walter

Hasty was trending in the wrong direction over the last few weeks, and his injury means he can be dropped in typical leagues. With Raheem Mostert, Jeff Wilson and Tevin Coleman out, it should mean a big workload for McKinnon going forward, at least until Mostert is able to return. Fullback Juszczyk could get more involved and Walter is a name to keep an eye out for despite being at the bottom of the depth chart.

San Francisco 49ers running back Raheem Mostert has finalized a new contract with the team, his agent announced Monday.

Earlier this month, agent Brett Tessler announced he had requested that the 49ers trade his client because of unproductive contract talks. However, the situation changed on Monday as Tessler tweeted:

"Just finalized a new deal for Raheem Mostert with the San Francisco 49ers. Happy we got things worked out and looking forward to him having another great season there. Thanks to the organization for taking care of him."

Related players: Jerick McKinnon, Kyle Juszczyk, Tevin Coleman

Details of the contract were not immediately known, but before the deal, Mostert was scheduled to be paid a base salary of $2.575 million this season and was due $2.875 million in 2021 as part of a three-year contract he signed last year. Mostert will be a high-upside back in any given week, but given the nature of the 49ers’ hot-hand approach at the position, this may be a frustrating situation for fantasy owners.