The Chiefs ruled out RB Isiah Pacheco (knee) for Sunday's game vs. Denver.

LT Josh Simmons and WR Xavier Worthy are off the injury report.

Related Players: Kareem Hunt, Brashard Smith, Rashee Rice, Hollywood Brown, JuJu Smith-Schuster, Travis Kelce

With Pacheco set to miss more time, Hunt should be considered a fringe RB2/3, while Smith is more of a desperation RB4.

While Rice is still in WR1 territory, Brown is pushed out of potential WR4 range.

George Karlaftis and Xavier Worthy were limited in practice today.

Isiah Pacheco did not practice.

Related Players: Kareem Hunt, Brashard Smith, Rashee Rice, Hollywood Brown, JuJu Smith-Schuster, Travis Kelce

With Pacheco set to miss more time, Hunt should be considered a fringe RB2/3, while Smith is more of a desperation RB4.

While Rice would still sit in WR1 territory whether or not Worthy plays, Brown would elevate into more of a boom/bust WR4 role.

WR Hollywood Brown (ill), RB Isiah Pacheco (knee) and LT Josh Simmons (personal) will not practice on Wednesday ahead of Buffalo. As described by Andy Reid, RG Trey Smith will give it a "whirl" after going through the walkthrough.

Related Players: Kareem Hunt, Brashard Smith

Given that Brown's absence is due to illness, we'll hold off making any sweeping judgments about his absence.

As for Pacheco, it seems very unlikely he'll play in Week 9, leaving Hunt (RB2) and Smith (low-end RB3) in the mix as fantasy pieces.

Before the practice, coach Andy Reid said Rashee Rice will make his season debut Sunday when the Chiefs host the Las Vegas Raiders (1 p.m. ET, CBS).

"How many snaps he gets, [I don't know]," Reid said of Rice. "He's excited to be back in and going. I think getting through practices [this week] will be good for him to get into the swing of things. He's been working hard. He's in good shape."

Related Players: Xavier Worthy, Hollywood Brown, Tyquan Thornton, Travis Kelce

We could see a bit of a snap count for Rice, but we wouldn't assume they would be putting him on the field if they weren't going to use him. Even if he is limited, this should be quite the upgrade for Patrick Mahomes, while the intermediate work for Kelce could end up taking a backseat to the far more explosive option. Rice should be considered more of a fantasy WR2 than WR1 as he ramps up.

Chiefs WR Xavier Worthy has no injury designation for Sunday night’s game vs. the Lions and is good to go.

Related Players: Hollywood Brown, Tyquan Thornton, JuJu Smith-Schuster

Worthy has made an immediate impact on the Chiefs offense, combing for 17 targets in his first two games back. In a nice matchup against the Lions in Week 6, consider him a fringe WR1/2.

Chiefs WR Xavier Worthy (shoulder) is off the injury report and officially good to go Sunday vs. Baltimore.

Related Players: Tyquan Thornton, JuJu Smith-Schuster, Hollywood Brown, Travis Kelce

Since his massive 16-target performance after Worthy went down in Week 1, Brown has been completely forgettable in his two chances to earn more work since. Push Worthy up into the WR3 range now that he's been completely cleared.

Chiefs listed WR Xavier Worthy as a full participant in today’s practice, putting him on track to play Sunday against Baltimore.

Related Players: Tyquan Thornton, JuJu Smith-Schuster, Hollywood Brown, Travis Kelce

Since his massive 16-target performance after Worthy went down in Week 1, Brown has been completely forgettable in his two chances to earn more work since. If Worthy is looking close to 100% this early in the week, we should definitely consider him further up our rankings than if he weren't a full participant until Friday. Push him up into the WR2/3 range if he is completely cleared ahead of the weekend.

Ahead of Sunday's game against the Baltimore Ravens (4:25 p.m. ET, CBS), the Chiefs are optimistic Xavier Worthy will be able to play a limited role for the offense while wearing a small harness. Patrick Mahomes and HC Andy Reid say they are confident the Chiefs can continue to be successful on deep passes with Tyquan Thornton running routes alongside Worthy. By Week 7, Mahomes' dropbacks could feature him having a combination of quality options -- such as Travis Kelce, Thornton, Worthy, Rashee Rice and Hollywood Brown.

Slowly the Chiefs offense is starting to get healthy and back to what everyone envisioned at the start of the season. Worthy has a chance to play in Week 4 but the team is already saying he'll be limited, so fantasy owners will want to monitor just how much Worthy will play or maybe in what situations.

Sources classify Xavier Worthy as "50-50" to return for Week 3 against the Giants, noting optimism but also the need to see him handle a fuller practice workload. "Have to see how he looks with real practice reps," the source said. Worthy practiced in a limited capacity Thursday and Friday of last week, and the Chiefs will ramp up his workload coming off the shoulder injury.

Related Players: Hollywood Brown, Tyquan Thornton, JuJu Smith-Schuster, Jason Brownlee, Travis Kelce

It would be hard to trust Worthy in fantasy lineups if he's still on 50-50 this late in the week, so he's best left on benches even if he does suit up. Brown should continue to be considered a WR3 regardless, while the rest of the WR room are only suggested in very deep leagues.

Chiefs WR Xavier Worthy (shoulder) is officially doubtful for Sunday vs. the Eagles.

Related Players: Hollywood Brown, JuJu Smith-Schuster, Tyquan Thornton, Travis Kelce

Brown is the most obvious beneficiary and should be considered a fringe WR2/3. Smith-Schuster will operate underneath with a limited ceiling, while Thornton is a desperation boom/bust play.