ESPN's Adam Schefter reports that the 49ers have closed team facilities Wednesday after wide receiver Kendrick Bourne testied positive for COVID-19. Schefter notes that as of right now, Thursday Night Football between the 49ers and Packers is still set to be played tomorrow night.

Thursday Night Football is still tentatively set for tomorrow, but that could change later today in light of Bourne's positive test and the possibility he had contact with other players or staff. Fantasy managers with 49ers or Packers will need to monitor the news over the next 24 hours to make sure the game is played as scheduled.

Wide receiver Deebo Samuel and running back Jeff Wilson Jr., both of whom played major roles in Sunday's 33-6 win against the New England Patriots, are expected to miss extended time, according to coach Kyle Shanahan.

Related players: Kendrick Bourne, Jerick McKinnon, JaMycal Hasty

Samuel is dealing with a left hamstring strain and will "most likely" miss this week's game at the Seattle Seahawks and next week's home contest against the Green Bay Packers, according to Shanahan. Wilson is the latest 49er to suffer a high left ankle sprain and is expected to go on injured reserve this week, which means he will have to miss at least the next three games, the story said. As we reported just a bit ago, Bourne looks like he'll take over for Samuel while McKinnon could jump back into a bigger role at RB. The 49ers said they purposely cut back on McKinnon's workload this past week (surprise fantasy owners) but it should mean he gets a bigger role this week. However, the rookie Hasty has looked good and could take some of the workload at RB.

If Deebo Samuel (hamstring) can't play against the Seahawks, Kendrick Bourne likely would start opposite Brandon Aiyuk, and Dante Pettis likely would be in uniform for the first time in three weeks. The 49ers also have the option of elevating Kevin White or River Cracraft from the practice squad.

The injury happened on a run play. Samuel was second among WRs in snaps behind Aiyuk and from what the article said, Bourne would step into Samuel's role if the injury keeps him out in Week 8.

Remember, George Kittle set the single-season record for receiving yards by a tight end in a season in which Nick Mullens started the last eight games. Those were mostly run-after-catch yards.

Obviously, Kittle (knee) is iffy for Sunday’s game on MetLife Stadium’s bouncy-house field. If he’s not there, I’d imagine Jordan Reed is a frequent target.

Kendrick Bourne and Dante Pettis also had good production when Mullens was under center in 2018. Mullens also threw to Matt Breida out of the backfield quite a bit, which makes Mullens a potentially good pairing with Jerick McKinnon.

Of Bourne’s 487 receiving yards, 296 came when Mullens was the quarterback. Pettis had his best NFL stretch with Mullens throwing to him — 371 of his 467 receiving yards came in the last eight games of 2018, the story said. With RBs Raheem Mostert and Tevin Coleman likely missing Week 3, McKinnon is potentially a nice play this week at RB.

The end-of-game sequence was symbolic of an outing in which Jimmy Garoppolo seldom threw to his wide receivers and often was a tick off when he did. Three plays before the final incompletion to Trent Taylor, Garoppolo saw Kendrick Bourne all alone in the right corner of the end zone. His throw had too much loft, however, allowing cornerback Patrick Peterson to recover and break up the play.

Bourne and Taylor combined for four catches for 41 yards and were the only 49ers wideouts to catch a pass. The team’s would-be starters, Deebo Samuel and Brandon Aiyuk, were ruled out with injuries, and Samuel won’t be back until October at the earliest after going on injured reserve on Saturday.

The 9ers mainly targeted tight ends and running backs the story said. The story also added Aiyuk, who is recovering from a hamstring strain, was close to playing against the Cardinals.

Rookie wide receiver Brandon Aiyuk clearly established himself among the top – if not the top – wide receiver on the field during the first week of 49ers camp.

But Aiyuk’s status for the short term now is tenuous due to a hamstring injury he sustained during practice on Sunday morning.

Related players: Kendrick Bourne, Deebo Samuel, Trent Taylor

The 49ers did not immediately provide an update on Aiyuk's status. Aiyuk and Bourne have established themselves as the top wide receivers with Taylor consistently playing in the slot. The 49ers hope to have Deebo Samuel back for the regular-season opener after he underwent surgery in June to repair a Jones fracture.