Squirrel Patrol's Week 10 NFL Main Slate DFS GPP Picks

Week 10 brings a 10-game main slate on Sunday, kicking off at 1 PM ET, with DraftKings featuring multiple Millionaire Maker contests and FanDuel offering a contest with a $1 million total prize pool. SF/DAL carries the highest total on the slate at 55.5, with the 49ers favored by 4, followed by BUF/NYJ at 51.0, with the Bills favored by 7.5, and CAR/NO at 49.0, with the Saints favored by 2.5. KC/ATL is next at 47.0, with the Chiefs favored by 3, and the Jaguars (-10.5) are the biggest favorites on the slate in Tennessee. Three games kick off in the late window, with SEA/LV and LAR/ARI at 4:05 PM ET and SF/DAL at 4:25 PM ET.

CAR/NO is the game I expect the field to flock to. It is easy to stack and has a decent total, and our ownership projections already show it, with Tyler Shough the most popular quarterback on DraftKings, Chuba Hubbard the second-most popular running back on FanDuel, and Chris Olave tied for the most popular receiver on DraftKings. I think that game will see too much ownership, so I may end up under the field on it. I prefer SF/DAL, BUF/NYJ, and KC/ATL, where Patrick Mahomes gets to play indoors.

The biggest injury question is Kenneth Walker III (groin), who is questionable after sitting out Friday's practice. If Walker is ruled out, rookie Emmett Johnson becomes a top play on both sites at $5,100 on FanDuel and $4,700 on DraftKings. George Pickens (hamstring) was limited in practice after missing last week's game, and I'm writing this assuming he plays, while Jake Ferguson (knee) is out for Dallas. Mike Evans (Achilles) has not practiced this week for San Francisco, and Deebo Samuel (hamstring) returned to limited practices after missing three games. Bhayshul Tuten (ankle/foot) is off Jacksonville's final injury report after missing practice Wednesday and Thursday, and Woody Marks (knee) is off Houston's after a full practice Friday. Kirk Cousins starts for Minnesota after Tuesday's trade from Las Vegas, Deshaun Watson returns for Cleveland, Drew Lock starts again for Seattle, and Kyle McCord makes his first NFL start for Miami, with Malik Willis on injured reserve.

Let's break down the positions, spotlight some of the best DFS options, and map out a path to the top of the leaderboards this Sunday.

Quarterbacks

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