49ers WR Quinton Patton (foot) was ruled out for Week 1...

Dalton Schultz practiced fully Friday and has no injury designation against the Giants. Tank Dell is questionable after three full practices and still needs to be activated from injured reserve.

Related Players: Foster Moreau, Brevin Jordan, Cade Stover, Nico Collins, Jaylin Noel, Marvin Harrison Jr., Xavier Hutchinson, Kayshon Boutte, C.J. Stroud, Woody Marks

Schultz is available as a TE2 or bye-week streamer, while Moreau and Jordan lose their potential injury-replacement appeal. Dell is better treated as a stash than an immediate start if activated. His return would add competition for Noel, Harrison, and Houston’s depth receivers; Collins remains the clear starting option.

Tyjae Spears is questionable against Cleveland with a knee injury. He was limited Friday after practicing fully Thursday.

Related Players: Tony Pollard, Julius Chestnut, Cam Ward

If Spears misses Sunday, Pollard would become a stronger RB2 with a chance to add receiving work to his rushing workload. Spears would be a risky FLEX even if active. Chestnut could pick up some reserve work, but fantasy managers should generally be able to find a better waiver-wire option.

DeVonta Smith, Dontayvion Wicks and Dallas Goedert did not practice Friday, their second consecutive absences this week. Philadelphia holds its final practice Saturday before facing Dallas on Monday night.

Related Players: Hollywood Brown, Makai Lemon, Darius Cooper, Elijah Moore, Johnny Mundt, Grant Calcaterra, Eli Stowers, Tanner McKee, Saquon Barkley

Managers relying on any of the three should secure a Monday replacement before Sunday’s games begin. If Smith and Wicks sit, Brown would have a path to WR3 value, with Lemon entering the deeper FLEX conversation. Cooper and Moore would be more speculative plays. Goedert’s absence would create opportunity at tight end, but Calcaterra and Stowers still need activation from injured reserve; Mundt should not be treated as an automatic streaming answer.