There was an update on running back Raheem Mostert, who also left the game at halftime. Shanahan said he has an MCL sprain and is likely to miss Week Three.

Related players: Tevin Coleman, Jerick McKinnon, Jeff Wilson

There was no update for Coleman in the story, who also left the game. The two injuries left McKinnon and Wilson to handle the workload, and that would likely be the case in Week 3 if Coleman is out as well. We'll continue to monitor but McKinnon is looking like an interesting pickup this week as the 9ers visit the Giants.

Raheem Mostert sustained a mild MCL sprain during Sunday's 31-13 road victory against the Jets, Adam Schefter of ESPN reports.

Backfield mate Tevin Coleman, who also hurt his knee Sunday.

Related players: Jerick McKinnon, Jeff Wilson

Mostert departed the game in the second quarter, but not before accumulating 107 yards from scrimmage on 10 touche. Coleman had 12 yards on 14 carries. Because of those injuries, McKinnon (three rushes for 77 yards and a score) and Wilson (two runs for three yards) rounded out the 49ers' healthy running backs, the story said. Remember, the team signed McKinnon to be the go-to back a couple of years ago before getting hurt, so he could be finally getting his chance if Mostert and Coleman miss time.

I wouldn’t assume Raheem Mostert starts. Once he does, it will be the first start of his career. As dominant as Mostert was toward the end of the season, Kyle Shanahan and Bobby Turner liked starting games with Tevin Coleman because he’s a little bigger and more physical runner than the others.

So my guess is that the arrangement will be the same as last season: Coleman starts, with Turner then using his feel for who’s hot that day dictating the snap loads for the rest of the game.

Related players: Jerick McKinnon, Jeff Wilson

The wild card, of course, is McKinnon, the author went on to say. It’s possible that he becomes the preferred tailback on third downs. There also could be instances in which he and another tailback are in the formation with McKinnon lining up in the slot or even out wide. The story added if McKinnon's knee isn't as good as the early reports, Wilson enters the picture.

According to Albert Breer of The Monday Morning Quarterback, San Francisco 49ers running back Jeffrey Wilson has landed on the reserve/COVID list.

This news does not mean that Jeff Wilson has contracted the virus, but does mean that it is believed he has at the very least come in close contact with some who has. Missed camp time will be a detriment to his hopes of carving out a role in the backfield, but expanded roster almost ensure that he will be kept around for his special teams ability. Jeffrey Wilson’s deep league stock took a mini hit when Raheem Mostert and the 49ers agreed to a revised deal, as Mostert holding out or being traded would have led to a clearer path to Wilson working his way to consistent fantasy relevance.

Shanahan is optimistic that OT Joe Staley (finger), RB Matt Breida (ankle) and DE Dee Ford (hamstring) will return this week. Less so for WR Dante Pettis (knee). And DL Jullian Taylor (ligament sprain) could miss some time.

Related players: Tevin Coleman, Raheem Mostert, Jeff Wilson

Despite the success of the 49ers, from a fantasy angle, their RBs have been tough to predict. It was Mostert who stood this past week but he still split work with Coleman. Wilson has been the goal line back and Breida would likely take his spot. Even then it's a three-headed monster at RB if Breida is back this week.