Eagles WR DeVonta Smith not expected to play in Week 4

McConkey did not practice Thursday after being limited Wednesday by a foot injury. ESPN’s Kris Rhim also observed McConkey leaving the locker room with a noticeable limp, suggesting his downgrade was more than routine workload management.

Related Players: Quentin Johnston, Tre' Harris, Brenen Thompson, Derius Davis, Oronde Gadsden

The downgrade and visible limp make McConkey’s Friday participation especially important. If he cannot play, Johnston and Harris would become the Chargers’ primary WR options, while Davis would be a candidate for additional slot reps. Thompson has also missed both practices this week, leaving Los Angeles short on healthy depth. Johnston and Harris would enter the flex and DFS conversation, while Gadsden could receive additional short-area targets. McConkey managers should prepare a late-window replacement.

Jefferson did not practice Thursday because of the ankle sprain he suffered in Week 3, giving him consecutive DNPs to begin the week.

Head coach Kevin O’Connell previously called Jefferson day-to-day and said he was improving, but added that Minnesota would not rush him back until he could play like himself. Friday’s practice and final designation will provide the clearest

Related Players: Jordan Addison, Jauan Jennings, Tai Felton, Myles Price, T.J. Hockenson

Consecutive absences put Jefferson’s availability in legitimate doubt, although a limited Friday practice could keep him on track to play. Because Minnesota kicks off at 4:05 p.m. ET, managers should identify a late-window alternative before Sunday. Addison would become a strong WR2 if Jefferson sits, with Hockenson positioned for additional targets. Jennings, Felton and Price would compete for the remaining WR reps, but none would immediately become a dependable season-long option. Jennings and Felton would carry some deep-league and DFS appeal.

49ers signed WR Brandin Cooks to the 53-man roster. They have brought WR Malik Turner back to the practice squad to take his place there.

Awaiting word on corresponding move but did not see WR KhaDarel Hodge (knee) during early open portion of practice.

Related Players: Mike Evans, Deebo Samuel, Jordan Watkins, Jacob Cowing, KhaDarel Hodge

Cooks is likely not a standard-league waiver target, but his promotion puts him within striking distance of an immediate role. If Evans cannot play, San Francisco would be left distributing WR snaps behind Samuel among Watkins, Cowing, and Cooks, with Hodge potentially no longer on the roster. Cooks’ experience could help him earn routes quickly, making him a viable salary-saving DFS consideration and a name to monitor in exceptionally deep leagues. If Evans plays, Cooks will likely be limited to a rotational role, but there's also no telling how many snaps Evans will actually be tasked with.