49ers WR Ricky Pearsall misses Wednesday practice, QB Brock Purdy limited

Nov 05, 2025

Here’s the 49ers’ preliminary practice participation report via Shanahan:
No practice
WR Ricky Pearsall (knee)
DL Mykel Williams (knee)
Limited
QB Brock Purdy (toe)
C Jake Brendel (hamstring)
DE Bryce Huff (hamstring)
LB Dee Winters (knee)
LB Tatum Bethune (thigh)

Fantasy Impact:

We could honestly just copy-paste this exact same news blast every single week, and no one would notice.

As of now, there is no Week 10 fantasy impact, as the 49ers are in the same position they've been in since the end of September. We'll keep an eye on their practice reports to see if Purdy or Pearsall are able to suit up this weekend.

today

Rams WR Puka Nacua "good to go" for Week 10

Adam Schefter

29 minutes ago

Rams HC McVay Sean McVay told reporters that WR Puka Nacua should be good to play Sunday vs. the 49ers despite his rib injury.

Related Players: Davante Adams, Jordan Whittington

Fantasy Impact:

This is a fantastic spot for both Nacua and Adams against a depleted 49ers defense. Both can legitimately be considered fantasy WR1s.

Jets WR Garrett Wilson limited in Wednesday practice, QB Tyrod Taylor full participant

Brian Costello

1 hour ago

Garrett Wilson (knee) was limited in practice today. Tyrod Taylor (knee) was a full participant.

Fantasy Impact:

We should get used to the remaining Jets players taking quite a few days off while they go down with the sinking ship, so we'll hold off making sweeping fantasy judgements until/unless Wilson misses some more practice time.

Aaron Glenn has yet to make a Week 10 QB decision, but Taylor being a full participant means Justin Fields isn't in the clear.

Cardinals place QB Kyler Murray on IR

Adam Schefter

3 hours ago

Cardinals are placing QB Kyler Murray on injured reserve due to his foot injury, meaning he now will miss a minimum of four games.

Cardinals say this will give Murray the chance to focus on rehabbing his foot injury and that he is committed to getting back as soon as possible.

Related Players: Jacoby Brissett

Fantasy Impact:

We have to wonder if we see Murray for the rest of the season, and going even further, he could legitimately get moved to another team at season's end.

This isn't even necessarily a bad thing for Marvin Harrison Jr. or Trey McBride, who are still safe fantasy plays here in Week 10 and beyond.