Bengals RB Joe Mixon (ankle) is questionable for Week 5 against the Green Bay Packers.

Relared Players: Samaje Perine, Chris Evans

Safe to say Mixon is capital 'Q' questionable for Week 5. Samaje Perine would presumably be the lead rusher should Mixon sit out.

Cincinnati Bengals running back Joe Mixon missed Thursday's practice with an ankle injury.

It was initially feared that Mixon was week-to-week with the ankle injury, but the team refuted that, suggesting that Mixon's injury is more of the day-to-day variety. Whatever the case, Mixon has now missed the first two practices of the week and will likely need to practice in some fashion on Friday to be cleared for this weekend's contest against the Green Bay Packers. Samaje Perine and Chris Evans are expected to split touches if Mixon is ruled out.

Cincinnati Bengals running back Samaje Perine is likely to be used in a committee if Joe Mixon misses any games.

While some fantasy managers may have expected Perine to step into a featured role if Joe Mixon misses any time with injury, the more likely scenario appears to be Perine on early down and rookie Chris Evans on third downs. Evans is a former receiver with good route running skills and may prove to have a higher weekly floor due to his involvement in the passing game and insulation from gamescript. Mixon is dealing with an ankle injury and will likely need to practice in order to be cleared for Week 5. This is a situation for fantasy managers to monitor.

Despite not practicing Wednesday, Bengals HC Zac Taylor said RB Joe Mixon (ankle) is day-to-day.

Mixon was considered week-to-week prior to Wednesday but is now potentially in play Week 5 against Green Bay. Mixon's practice time matters on if he plays and if he shares his workload with Samaje Perine and Chris Evans.

But speaking to reporters on Monday afternoon, Cincinnati head coach Zac Taylor disputed the report, saying Joe Mixon is more day-to-day.

Related players: Samaje Perine, Chris Evans

Earlier on Monday, and as we reported, an ESPN report indicated Mixon is week-to-week with an ankle injury suffered against the Jaguars last Thursday, putting his Week 5 status in doubt. But this is at least some good news he could go in Week 5. Perine and Evans could also factor in more if the team doesn't want to give Mixon a big workload if he's not 100%. It will be worth monitoring this week and checking out the injury report on Wednesday.

Bengals’ RB Joe Mixon was diagnosed with a low-grade ankle sprain that will leave him week to week, per source.

Related players: Samaje Perine, Chris Evans

It was reported Mixon sat out the team's final drive on Thursday night against the Jags, and now it adds up as Mixon is dealing with a sprain. Perine touched the ball four times on that final drive and had also seen time on third down. If Mixon has to miss time, Perine could certainly see an uptick on touches and snaps. Evans would be next up and likely would be a factor in the game plan as well if Mixon is out.

I thought it was Joe Burrow’s best day yet. Confident, scrambling at times, and making good intermediate throws for 1st downs. By my count, 10-for-15 in full team drills including a drive that ended with a short Joe Mixon TD run.

I also thought it was Ja’Marr Chase’s best practice so far with a TD in 7-on-7s.

It's good to see from the Bengals, as we've seen several reports this summer about their offense struggling. We also had a report about Chase on Monday that painted a picture of him struggling with separation and drops. So it's perhaps a turning point for the Bengals today.

As expected, Bengals RB Joe Mixon will not play this week.

Mixon hasn't played since Week 6 against Indy, dealing with a foot injury. While he didn't light up the fantasy scoreboard most weeks, he did average 19 carries a game. He averaged 71 rushing yards a game but most of that came from a 151-yard performance against the Jags. His second highest rushing total was 69 yards in Week 1. He averaged 3.5 catches a game as well, which came with QB Joe Burrow under center. It will be tough to trust Mixon in 2021 but with Burrow back and the volume Mixon got this season, he'll likely be a highly-desired fantasy pick once again next summer.

Bengals Head Coach Zac Taylor ruled running back Joe Mixon out for Week 16 due to his foot injury.

The news is not surprising as this will mark Mixon's ninth consecutive missed game and it certainly looks like the Bengals have shut him down for the season. Giovani Bernard will continue to handle the majority of the backfield work in Cincinnati with Samaje Perine and rookie Trayveon Williams mixing in for occasional touches.

Cincinnati Bengals head coach suggested running back Joe Mixon will not play against the Steelers in Week 15. When asked if Mixon would play this week, Zac Taylor said "Check back next week".

Joe Mixon has not been officially ruled out, but head coach Zac Taylor comments suggest that he will be officially ruled out on Friday. Mixon was disappointing when healthy, but remains one of the most talented running backs in the league. Gio Bernard, Samaje Perine, and Traveon Williams will share touches in his absence. Gio is our 37th ranked running back for Week 15.