Bills RB James Cook is good to go Sunday vs. Dolphins.

Buffalo ruled out DL AJ Epenesa and LB Shaq Thompson.

DT Daquan Jones, WR Josh Palmer + CBs Taron Johnson & Christian Benford are questionable.

Related Players: Ray Davis, Ty Johnson

Cook is cleared ahead of a fantastic matchup, putting him right back into RB1 consideration.

Bills CB Christian Benford was not on the practice field Thursday. He popped up on the injury report Wednesday with a groin injury.

RB James Cook, DE Joey Bosa, DT DaQuan Jones and NCB Taron Johnson all returned to practice today.

Related Players: Ray Davis, Ty Johnson

Cook should be good to go, as we're assuming this was at least a "limited" practice. If he were to miss Week 10, expect Davis to get a large majority of the early-down work, with Johnson taking on an even bigger third-down role.

Bills RB James Cook did not practice today due to foot and ankle injuries.

Related Players: Ray Davis, Ty Johnson

Still plenty of the week left to get right, but we'll keep an eye on things. If he were to miss Week 10, expect Davis to get a large majority of the early-down work, with Johnson taking on an even bigger third-down role.

Bills RB James Cook (hamstring) is off the injury report and good to go Sunday vs. the Jets.

Related Players: Ray Davis, Ty Johnson

All systems go for James Cook as a high-end RB2 here. Keep Davis in the desperation RB4 range.

Perhaps Ray Davis could be a bit more of a factor, but it wouldn't be a surprise to see a similar split to last season among the Bills' three backs. The team put James Cook on the field for 47.6% of offensive snaps, with Davis getting opportunities (24.3%) and Ty Johnson seeing the field often on third downs (29%). Despite Cook "holding in" for much of camp before reaching a contract extension on Wednesday, the Bills did not show anything in practice to indicate a different approach this season.

Looks like Davis will continue to be mostly an arbitrage play in fantasy, though we have to assume some regression from Cook's 16 rushing touchdowns, so maybe the sophomore can snag some of those. He's still an interesting pick for RB-needy teams in the double-digit rounds.

Bills now have officially signed RB James Cook to a four-year contract extension through 2029.

Related Players: Ray Davis, Ty Johnson

It's a four-year, $48M extension after Cook scored 18 combined touchdowns last season. We can still expect Davis and Johnson to rotate in (and Josh Allen could always take some of those rushing touchdowns for himself), but Cook remains a very solid RB2 option in 2025.

Buffalo Pro-Bowl running back James Cook did not report to the start of the Bills’ voluntary offseason program. Cook is heading into the final year of his rookie contract and would like a new deal.

Related Players: Ray Davis, Ty Johnson, Darrynton Evans, Frank Gore Jr.

The Bills are equipped to head into the season sans Cook, but no one behind him on the depth chart has the same do-it-all functionality as the RB1. We'll keep an eye on this, but it's still too early in the process to panic about Cook's availability.

Running back Ty Johnson is returning to the Bills on a two-year deal, per source.

Johnson emerged as a versatile third-down back for Buffalo, now gets rewarded.

Related Players: James Cook, Ray Davis

While Johnson isn't a fantasy asset on his own, his re-signing could block further playing time for sophomore Ray Davis. They will both continue to rotate in behind Cook, who consistently performed as a back-end RB1 in fantasy last season.

Another Monday night inactive surprise at RB: James Cook is out tonight due to his toe injury, per source. It’s the first NFL game in three seasons that Cook has missed.

Related players: Ray Davis, Ty Johnson, Frank Gore, Jr.

Cook is unable to go tonight. The Bills added to that speculation a few hours ago when they announced rookie RB Gore would suit up. Davis could be in line for the early down work with Johnson getting passing downs. Gore could also mix in as well. It will be a tough matchup against the Jets on the road.

RB James Cook (foot/toe) remained sidelined at Thursday’s Bills practice. Cook’s second straight absence. Looking less likely that he will play against the Jets, but the longer week gives him a better chance.

Related Players: Ray Davis, Ty Johnson

If Cook were to miss Week 6, it's hard to say how the backfield load would get divvied up. Obviously Ty Johnson has more experience than rookie Ray Davis, but it's the latter who leads in the carry department, 26-10. Davis feels like the better pick-up, but neither one would carry a full bellcow load regardless, which makes them iffy spot-starts.