RB Isaac Guerendo returned to practice and had an active day. So as Patrick Taylor and Corey Kiner exit due to injuries, Guerendo comes back.

Related players: Christian McCaffrey, Jordan James, Jeff Wilson

It's always news when a potential CMC handcuff is back on the field. Guerendo missed time with a shoulder injury and the rookie James is still out, so Guerendo could secure his RB2 role behind McCaffrey, who has looked good and close to his 2023 form so far in camp, according to reports. Still, those owning CMC likely want to have protection - just in case. Guerendo proved he can do the job last season.

49ers rookie RB Jordan James broke his finger and is getting surgery. Will be out "a couple weeks", Shanahan said

Related Players: Christian McCaffrey, Isaac Guerendo, Corey Kiner, Ameer Abdullah

Guerendo is already sidelined with a shoulder injury so things are pretty thin in the RB room right now. If CMC wasn't already slated for a giant workload, that looks just about locked in at this point. He's an easy first-round click.

49ers RB Isaac Guerendo is expected to miss “a few weeks” with a shoulder injury, per Kyle Shanahan.

Related players: Christian McCaffrey, Jordan James, Patrick Taylor

With Guerendo missing that much time, it could open the door for the rookie James, who has already looked good in camp, according to those who follow the team. Guerendo certainly did enough last year as a rookie to still be in the mix. The 49ers are a CMC injury away from having someone else step in and get an RB1 workload, so fantasy owners will want to keep an eye on the team's RB2 battle in camp.