Rams rookie running back Kyren Williams is set to miss a chunk of time after having surgery to repair a high-ankle sprain he suffered in the season opener and the team announced on Tuesday that he’ll be going on injured reserve as he recovers.

Williams will miss at least four games as a result of going on the list and word last Friday was that he should miss 6-8 weeks. Williams was injured covering a kickoff on the only snap he played in his first NFL regular season game.

Related players: Cam Akers, Darrell Williams, Jake Funk

After Akers disappeared in Week 1, many thought Williams could eventually get some work out of the backfield for the Rams. That will at least be put on hold until he's back. With Akers seemingly in the doghouse, it looks like Henderson should be the team's RB1 at least for now.

Both Cam Akers and Darrell Henderson are dealing with what Sean McVay describes as “soft tissue” injuries.

Related players: Kyren Williams, Jake Funk

Both are being held out of practice until both are at full speed in a team setting, according to the rest of the tweet. Williams and Funk practiced and took the main workload, the tweet went on to say. The good news here, according to other reports, the injuries don't appear to be serious. However these are the type of injuries that can linger so it's worth monitoring.

Rams coach Sean McVay says that RB Darrell Henderson has a rib cartilage injury.

Related players: Sony Michel, Jake Funk

The tweet went on to say the team has hope and optimism for him to play Week 3, and will be checking in again Friday. The Rams host the Bucs in a late afternoon game. Michel would likely get a bulk of the work if Henderson can't go. He carried 10 times for 46 yards last week.

Xavier Jones (ankle) was waived/injured by the Rams on Tuesday, Stu Jackson of the Rams' official site reports.

The Rams backfield has been beset by injuries this summer, with Cam Akers (Achills) and Raymond Calais (foot) already on IR and Jones set to join them.

Related players: Darrell Henderson, Sony Michel, Jake Funk

Assuming Jones clears waivers, he will have a chance to return at some point this season once his left ankle is healthy. For now, Los Angeles will rely on Henderson (thumb), Sony Michel and Jake Funk at running back.

A source was able to confirm that RB Darrell Henderson sprained his thumb.

Related players: Xavier Jones, Jake Funk

Rodrigue went on to tweet there is no ligament damage. It's great news for Henderson as it could have been a lot worse. According to the source, Henderson is day to day; he left Monday's practice partway through and did not return. It's probably still a good idea to back up Henderson with Jones, who has made a name for himself in camp this summer with the injury to Cam Akers.

Darrell Henderson hurt his thumb, per McVay (who is literally just off the field) and he doesn’t have a sense of how bad it is/next steps yet. Henderson did not return to practice.

Related players: Xavier Jones, Jake Funk

This is obviously something to keep an eye on. Either way, if you have stock in Henderson it seems like a really good idea to back him up with Jones, who is having a good camp.

Remember, the goal is going to be to maximize Darrell Henderson’s availability, and his ability.

Related players: Xavier Jones, Jake Funk

The story went on to say it will be a "likely fluid, likely situational snap count" in which he’ll be complemented by Jones and Funk. Henderson has continued to look good in camp but so have the other backs. It sounds like the Rams want to do their best to keep Henderson healthy for the long haul. Jones seems like he'll be a solid handcuff for Henderson owners.

Darrell Henderson Jr. is penciled in as the Rams’ starting running back after Cam Akers tore his Achilles before training camp. That much we know.

What isn’t as clear is who will back up Henderson.

The Rams have Xavier Jones, Jake Funk, Raymond Calais and Otis Anderson on the 90-man roster right now, but they’ve combined to play zero offensive snaps in their NFL careers. So needless to say, there isn’t much experience at running back behind Henderson.

The story said Jones is the favorite to back him up after sticking with the Rams last season as an undrafted rookie. He’s getting more work in camp this year due to Akers’ absence and though it’s early, Sean McVay is encouraged by what he’s seen from Jones, as well as the Rams’ other backup running backs.