At the league meeting this week, 49ers GM John Lynch said he expected WR Brandon Aiyuk to stick in 2025. His 2026 option-bonus guarantee triggered yesterday. He’s owed $24.875m this year, $27m in ’26. The $76m that was effectively guaranteed at signing is now fully guaranteed.

Related Players: Jauan Jennings, Ricky Pearsall, Demarcus Robinson, Jacob Cowing

This is likely the best case sceanrio for the 49ers and Brock Purdy's fantasy aspirations, but it's hard to say if it's a positive for Aiyuk. That would have all depended on his eventual landing spot, but it seems like we'll have to wait at least one more year for that shoe to drop. Consider the vet somewhere in the back-end WR3 range for now, with Jennings a tier or two above that.

John Lynch on KNBR said Jauan Jennings is doubtful with his groin injury this week.

Related Players: Deebo Samuel, Ricky Pearsall, Jacob Cowing, George Kittle

If Deebo is good to go, we can assume the 49ers will be heavily targeting himself and Kittle this week in a good matchup. This makes both huge assets to fantasy squads, and rookie Ricky Pearsall is an interesting deep-league play in his second career game.

According to multiple reports, Deebo Samuel has been discharged from the hospital. Samuel left Sunday’s loss to the Chiefs with an illness and went to the hospital later that night.

Related players: Jauan Jennings, Ricky Pearsall, Chris Conley, Ronnie Bell, Jacob Cowing

Head coach Kyle Shanahan said that Samuel had fluid in his lungs and described his condition as pneumonia. Shanahan said that the team will see how Samuel recovers over the coming days, but owners should probably have other plans in place, especially because the Niners are at home against the Cowboys on Sunday night.

The illness that sidelined Deebo Samuel yesterday is pneumonia. He's in the hospital.

Related players: Brandon Aiyuk, Jauan Jennings, Ricky Pearsall, Chris Conley, Ronnie Bell, Jacob Cowing, George Kittle

When the team realized Deebo had fluid in his lungs, he was sent to the hospital, Lombardi said in another post. Another beat writer, Nick Wagoner, reported Samuel was struggling to breathe which is why he wasn't in the game very long. Aiyuk is out for the season so the Niners now find themselves very thin at the WR position. There is no timetable for Samuel's return at this point. Reports say the team should get Jennings (hip) back in Week 8, but rookies like Pearsall and Cowing could very well be factors in the short term until Samuel is able to return.

Sources: 49ers WR Brandon Aiyuk suffered a season-ending knee injury on Sunday, tests confirmed.

Related players: Deebo Samuel, Jauan Jennings, Ricky Pearsall, Chris Conley, Ronnie Bell, Jacob Cowing, Trent Taylor, George Kittle, Christian McCaffrey

Anyone who held on to Jennings should be in good shape as he will likely slide in as the team's WR2 behind Deebo. Jennings didn't play in Week 7 because of a hip injury but the team is hoping to have in back for Week 8, according to reports. Pearsall was active for the first time and caught three balls for 21 yards. Cowing had two catches for 50 yards. Both rookies could be options behind Samuel, Kittle and likely Jennings, but may not be consistent fantasy producers. We reported McCaffrey is looking to return on Nov. 10 and it's possible he's counted on as a receiver more than a rusher once he's back.

49ers coach Kyle Shanahan told reporters that WR Deebo Samuel has a calf strain and will miss a few weeks. Another star injury for the Niners.

Related players: Brandon Aiyuk, Ricky Pearsall, Jauan Jennings, Ronnie Bell, Chris Conley, Jacob Cowing, George Kittle

It's a big blow to the Niners offense, which is already without Christian McCaffrey for an extended time. There was no mention on whether or not Deebo could end up on IR. Aiyuk should take over as the team's WR1, but who takes over as the WR2 is the bigger question. Kittle is likely next up after Aiyuk, which then leaves Jennings, Bell, Conley and Cowing at WR. Jennings is probably the leading candidate, but probably won't be a safe play in typical leagues. Cowing is a rookie who has stood out over the spring and summer and has been returning kicks, so it's possible he earns a bigger role with Deebo out.

The 49ers placed WR Ricky Pearsall on the reserve/non-football injury list after he suffered a gunshot wound in an attempted armed robbery over the weekend. Pearsall, the team's first-round pick, will miss at least the first four games.

Related players: Brandon Aiyuk, Deebo Samuel, Jauan Jennings, Ronnie Bell, Chris Conley, Jacob Cowing

The loss of Pearsall opens up the 49ers WR3 spot. However, with Aiyuk, Samuel and George Kittle, the Niners WR3 isn't always fantasy relevant. Despite that, Cowing could still be a name to keep an eye on. The rookie has generated a lot of positive press through camp this summer. However, guys like Jennings, Bell and Conley could also earn time in that WR3 role.

The standoff between receiver Brandon Aiyuk and the 49ers may be coming to a conclusion soon.

According to Ian Rapoport of NFL Media, the 49ers and Steelers have a deal for a potential Aiyuk trade in place. The Steelers also are “in a good place” with Aiyuk on a new contract. If the 49ers give their final sign-off, the deal will be done.

Related players: Ricky Pearsall, Jauan Jennings, Jacob Cowing, George Pickens, Van Jefferson, Roman Wilson, Calvin Austin III

The story went on to say San Francisco also has an offer out to Aiyuk on a long-term deal for him to remain with the club that, but to this point, Aiyuk has not accepted. The story added it’s currently unclear what Pittsburgh would send back to San Francisco in exchange for Aiyuk, but it would likely be a significant package. If the deal goes through, the Niners would be looking at Pearsall, Jenning and Cowing to move up the depth chart, while in Pittsburgh, Aiyuk and Pickens form the 1-2 punch.

WR Jacob Cowing (hamstring) will likely be out approx 10 days total

RB Isaac Guerendo (hamstring) will be out several weeks.

Related players: Elijah Mitchell, Ricky Pearsall, Jauan Jennings, Jordan Mason

It's always tough for rookies when they miss time in camp. Guerendo was said to be battling for the RB2 spot with the often-injured Mitchell. The Niners traded up to get Guerendo who was having a nice spring. Meanwhile at WR, the team got back Pearsall today but Cowing was trying to work his up with the depth chart as well.

First day of pads has some good news for the 49ers: Ricky Pearsall is in pads and practicing today.

Related players: Deebo Samuel, Brandon Aiyuk, Jauan Jennings, Jacob Cowing

It's good news Pearsall is back in the lineup for the 49ers. Aiyuk has been a hold-in so far at camp, so this is a chance for Pearsall to get some valuable work. The Aiyuk situation could be an interesting one as some say he could still be moved if the team can't get a deal done with him. If that happens, Pearsall's value could soar as a result. And that would also open the door a bit for Jennings and another rookie, Cowing. Assuming Aiyuk does return, Pearsall could be looking at a WR3 role.