Commanders QB Jayden Daniels ruled out for Week 4

Jadarian Price did not practice Thursday because of his chest injury after opening the week as a limited participant.

Seattle’s backfield is unusually unsettled. George Holani remained limited by a rib injury, while Zach Charbonnet returned to practice but cannot play until Week 5 at the earliest.

Related Players: Emanuel Wilson, George Holani, Zach Charbonnet

The midweek downgrade puts Price’s Week 4 availability in legitimate doubt, although Friday’s practice will be decisive. If Price cannot play, Wilson and Holani would likely share the backfield, assuming Holani’s rib injury does not keep him out. Wilson could handle more early-down work, while Holani has been Seattle’s preferred passing-down option. Neither backup should be treated as a confident starter until the final injury report clarifies the workload.

There is not much optimism Eagles receiver DeVonta Smith will play Sunday against the Rams, sources tell me and @MikeGarafolo.

Smith has been sidelined with a hamstring injury this week and the expectation is he won’t be able to go Sunday.

Related Players: Dontayvion Wicks, Makai Lemon, Darius Cooper, Zach Ertz, Dallas Goedert, Marquise Brown, Jalen Hurts, Saquon Barkley

Fantasy managers should plan to remove Smith from lineups. Wicks becomes Philadelphia’s most trustworthy available WR, with Lemon moving into deeper-league consideration and Cooper remaining a low-floor option. Ertz could also see additional targets if Goedert misses another game. The depleted pass-catching group lowers Hurts’ ceiling and could concentrate more of the offense around Barkley.

McConkey did not practice Thursday after being limited Wednesday by a foot injury. ESPN’s Kris Rhim also observed McConkey leaving the locker room with a noticeable limp, suggesting his downgrade was more than routine workload management.

Related Players: Quentin Johnston, Tre' Harris, Brenen Thompson, Derius Davis, Oronde Gadsden

The downgrade and visible limp make McConkey’s Friday participation especially important. If he cannot play, Johnston and Harris would become the Chargers’ primary WR options, while Davis would be a candidate for additional slot reps. Thompson has also missed both practices this week, leaving Los Angeles short on healthy depth. Johnston and Harris would enter the flex and DFS conversation, while Gadsden could receive additional short-area targets. McConkey managers should prepare a late-window replacement.