Squirrel Patrol’s Week 8 NFL Main Slate DFS GPP Picks

Oct 24, 2025
Squirrel Patrol’s Week 8 NFL Main Slate DFS GPP Picks

Week 8 brings a 10-game main slate on Sunday, with our biggest set of bye weeks so far, but no international game and just one game on Monday night. We continue to see larger prize pools on both FanDuel and DraftKings, including two Millionaire Maker tournaments on DraftKings.

This week comes with some large spreads, with 7 of the 10 games holding a spread of 6.5 points or more. This is making it difficult to target full game environments, but creating some large team totals like the Colts (31.0), Ravens (28.0), and Broncos (27.0). Injuries continue to make an impact, with big names like A.J. Brown officially out, and Breece Hall and D’Andre Swift listed as Questionable.

Let’s break down the positions, spotlight some of the best DFS options, and map out a path to the top of the leaderboards this Sunday.

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