49ers QB Jimmy Garoppolo will undergo shoulder surgery that will sideline him until this summer.
Related Player: Trey Lance
Fantasy Impact:
Whether Jimmy G is a 49er come summer is still to be determined, it gives Trey Lance an opportunity to work with the team's offensive players as the QB1 as long as Garoppolo is out.
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Jalen Hurts will be out for the season after doctors discovered multiple blood clots in his lungs.
Related players: Tanner McKee, Joe Milton
Hurts's agent released a statement that Hurts will continue to be around the team and get blood thinners, and has no function limitations. He'll have to avoid football activities. She added she expects Hurts to make a full recovery and it will have no long-term effects, which is obviously great news. From a fantasy angle, McKee should remain the starter for at least the short term. While he flashed at times in a loss to the Panthers, overall it wasn't a great performance. The Eagles signed Joe Milton away from the Cowboys last week, and with Hurts now out for the year and the Eagles sitting at 2-4, it wouldn't be a surprise for the Eagles to see what they have with Milton. The team has not signed Hurts to an extension at this point and those who follow the team will say there is a chance the Eagles move on from Hurts after this year. GM Howie Roseman has set the team up with several early draft picks over the next two seasons so it's also possible they make a move for a QB in the draft.

Zonovan Knight rushed for 80 yards on just 15 carries.
Knight might've had more. He suffered full body cramps much of the second half, limiting his playing time (and perhaps taking a piece from the Cardinals' red zone package.)
Related players: Tyler Allgeier, Jeremiyah Love
With Love out, Allgeier looked to be a decent fantasy play in a tough matchup against the Rams. But it turned out to be Knight who was a much more efficient back. Allgeier had just 38 yards on 18 carries. If this seems familiar, Knight had a few games last season where he averaged over 4 YPC for the Cardinals and was likely at least a fantasy flex option. He added four TDs last season as well. If Love remains out, it seems like Knight will have a chance to at least earn some carries away from Allgeier.

The slumping Rams may be scrambling to find help at receiver.
Veteran Davante Adams suffered a non-contact injury to his left leg late in the game. He pulled up when running into the end zone on a pass route, reached for his left knee, and hobbled off the field for attention.
Coach Sean McVay wasn’t asked about Adams’s apparent injury during the post-game press conference, the story pointed out. But non-contact injuries aren't ever words you want to hear. There is no other information about Adams up to this point. If you like to look at doctors' comments on X, at this point it could be anything from a bone bruise and hyperextension to MCL sprain to meniscus tear to ACL. Obviously that's a wide variety, so we'll have to update as the Rams release more information.








