The Philadelphia Eagle will be without RB Jordan Howard (knee) for a second straight game, while RB Boston Scott (illness) and QB Jalen Hurts (ankle) are questionable.

Related Players: Gardner Minshew, Kenneth Gainwell Jr., Miles Sanders

Minshew took first-team reps for some of the week in case Hurts is out, which is no bueno. Scott should play but if he does not, Sanders should see majority of the running back work.

Eagles HC Nick Sirianni told reporters Friday that RB Jordan Howard (knee) will not play Week 12 against the New York Jets.

Related Players: Kenneth Gainwell, Miles Sanders, Boston Scott

Howard's absence opens the workload for Miles Sanders and maybe some carries for Boston Scott. It also means that Kenneth Gainwell will probably be active.

Jordan Howard has a knee sprain. He's most likely out this week, with a likely chance to play next week.

Related players: Miles Sanders Boston Scott, Kenneth Gainwell

Howard go twisted up pretty good on the play he got injured. It's a bit of a blow to the Eagles rushing attack, which has taken on a bigger role over the last several weeks. It should mean more work for Sanders, who just returned off the IR in Week 11. Scott should also factor in. Gainwell was a scratch in Week 11, but could get chances in Week 12 as well. It's a potentially nice matchup against the Giants in an early game.

Eagles HC Nick Sirianni told reporters Wednesday that RB Miles Sanders is the starting back when healthy. Sirianni also mentioned that Sanders could play Sunday if he looks good in practice.

Related Players: Boston Scott, Jordan Howard, Kenneth Gainwell Jr.

This backfield is about to get even more muddled. It is best to wait and see how the week's injury reports pan out before deciding to play any Eagles running back.

The Philadelphia Eagles have designated RB Miles Sanders (ankle) to return from IR.

Related Players: Jordan Howard, Boston Scott, Kenneth Gainwell Jr.

What is already a messy backfield will only get worse if/when Sanders returns in the next three weeks. Sanders may have lost his starting role with the emergence of Howard. The backfield touch distribution is going to be important to watch the first week Sanders is on the field.

It's no coincidence that Jalen Hurts' back-to-back solid outings coincide with a shift in offensive approach. HC Nick Sirianni, after neglecting the running backs for multiple weeks, went run-heavy the past two weeks against the Chargers and Detroit Lions (a 44-6 win). Consider: In Weeks 1-7, the backs totaled 96 carries (13.7 per game) for 444 yards and three touchdowns. In Weeks 8 and 9, those numbers skyrocketed to 66 carries (33 per game) for 258 yards and six touchdowns.

Related players: Jordan Howard, Boston Scott, Kenneth Gainwell

While Hurts has played better, his fantasy stats have taken a hit with more dependence on the running game. Hurts was accounting for nearly 90% of the Eagles' offense in the early going, the most in the NFL. The past couple of weeks have been easy street in comparison. He has averaged 15.5 pass attempts over the past two games compared to 34.5 attempts per game over the first seven weeks.

Eagles RB Miles Sanders (ankle) was placed on IR Friday. He is expected back after the minimum three games missed according to Ian Rapoport of the NFL Network.

Related Players: Kenneth Gainwell, Boston Scott

Gainwell and Scott has set roles for the next few weeks. Sanders's injury looked a lot worse than a three-week injury so a short IR stint is good news.

It appears the Eagles have dodged a bullet with Miles Sanders’ injury, although Nick Sirianni said it’s unlikely the 3rd-year running back will play this weekend.

Sanders suffered an ankle injury during the second quarter of the Eagles’ loss to the Raiders Sunday in Las Vegas and was carted off the field.

Related players: Kenneth Gainwell, Boston Scott

Sirianni said Monday the Eagles haven’t ruled Sanders out for their game Sunday against the Lions in Detroit, but it sounds like the odds are against him playing. Scott really saw his first significant action of the season after Sanders went down, so it's expected Gainwell gets a majority of the work based on Scott really not being a part of the game plan through the first seven games. Gainwell should be a popular pickup off the wire this week, but keep in mind the Eagles are not running the ball a whole lot.

Miles Sanders is getting X-rays done on his ankle, Sirianni said. The HC doesn’t believe anything is broken.

Related players: Kenneth Gainwell, Boston Scott

Sanders appeared to be on track for a solid fantasy outing before the injury. After leaving, he gave way to Gainwell and Scott. Gainwell was more involved in the passing game and also caught a TD pass for the team's first score. The passing game is normally where Scott has been involved, although Scott has been the workhorse in the past when Sanders has been out. Based on the first six games however, it would appear Gainwell has the most fantasy value to gain if Sanders has to miss time, as Scott had not really been involved in the offense before this week.

Nick Sirianni continues to play Kenneth Gainwell, and he continues to produce. Gainwell posted 89 yards from scrimmage after finishing with three carries for 31 yards and a score while catching six passes for 58 yards.

Related players: Miles Sanders, Boston Scott

He finished with the most receiving yards for an Eagles rookie running back since Scott in Week 17 of the 2019 season (84 yards). And speaking of Scott, it's been obvious Gainwell has passed Scott on the depth chart. As the story said, the Eagles have done an excellent job incorporating Gainwell into their offense, pretty much becoming the team's third-down back.