49ers hope Week 6 a potential return for WR Brandon Aiyuk (knee)

The 49ers don’t know for sure when wide receiver Brandon Aiyuk will be ready to return from last season’s knee injury. But it should be around the middle of the season.

Head coach Kyle Shanahan said today that there’s still a range of potential outcomes, but Week 6 is a potential target date he’s thinking of, not just for Aiyuk to make his 2025 debut, but also for quarterback Kurtis Rourke and safety Malik Mustapha, both of whom are also recovering from knee injuries.

Fantasy Impact: 

Shanahan said it could be Week 5, or Week 10, but he knows it won't be Week 1, according to the story. Aiyuk tore his ACL and MCL on October 20 of last season in a game against the Chiefs. The 49ers’ Week Six game is against the Buccaneers on Oct. 12, so if that’s Aiyuk’s return date, he would have missed just under a full year, the story pointed out.

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