Swift coming off the injury report so early in the week should point towards his typical role within the explosive offense.
Goedert looks to see in-game action for the first time since Week 9, and it comes against a huge divisional game against the Dallas Cowboys. His target share will always be somewhat capped with DeVonta Smith and A.J. Brown on the field, but he has notched two huge games for a struggling fantasy position: 8-117-1 in Week 5 and 5-77-1 in Week 7.
Jaylen Warren would be in for a full bellcow workload if Harris were to miss, though the Patriots' run defense has been stout, even with teams sticking to the ground against them. New England ranks third in rushing yards allowed and first in yards per carry (3.2). Regardless, Warren should maintain plenty of passing work to make him a solid RB2 without Najee Harris.
Phew. An offense that needs all the help/luck they can get is dug even deeper with the absence of some key pieces. Ezekiel Elliott should get a huge percentage of the running back work, but even that is likely to keep him in the low RB2 considerations.
Starting any Patriots wide receivers should be a stay-away at this point, though Hunter Henry can be considered a de facto TE streamer with the team rolling out an extreme lack of consistent options.