Peterman, a rookie fifth-round pick, replaced Taylor with less than five minutes remaining in a 47-10 loss to the New Orleans Saints. Taylor completed 9-of-18 passes for 56 yards before being benched.
Peterman went 7-for-9 for 79 yards and a touchdown over the final two drives for the Bills, who have lost two straight.
In the preseason, Peterman completed 43-of-79 passes (54.4% completion) for 453 yards and a 5.73 yards per attempt average. He threw one touchdown and no interceptions. The Chargers are a bad matchup for opposing quarterbacks (No. 9 in QB aFPA) but starting in Week 12, the Bills don't face a defense higher than No. 20 in that metric. If Peterman plays well, he could work his way into the streaming conversation.