49ers WR Brandon Aiyuk (knee) won't practice this week

Nov 10, 2025

Shanahan did not have any positive changes to report about wideout Brandon Aiyuk. He remains on the physically unable to perform list as a result of last season’s knee injury and Shanahan said he will not return to practice ahead of the team’s Week 11 game against the Cardinals.

Fantasy Impact:

The news on Aiyuk has been back and forth as of late. A few weeks ago a report said he wasn't close but a more recent report indicated he was getting closer. It will get tough and tougher to trust Aiyuk in fantasy lineups even if he does return sooner than later, especially as we head down the stretch of the fantasy regular season and then the fantasy playoffs.

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Jets WR Garrett Wilson (knee) to miss 3-4 weeks

Rich Cimini on X

1 hour ago

Bad news for the Jets offense: WR Garrett Wilson is expected to miss at least 3-4 weeks with a knee sprain, source says.

Fantasy Impact:

The Jets were hopeful Wilson could play this week, a Thursday night game, but that won't be the case. As the post added, the good news is no surgery is needed, just rehab. Wilson's injury could bring him back for the fantasy playoffs, but he'll be tough to trust if Justin Fields is still under center. A lot could happen at QB for the Jets between now and Wilson's potential return.

Chiefs RB Isiah Pacheco (knee) may 'take more time'

Pete Sweeney on X

1 hour ago

Reid nudged that RB Isiah Pacheco (knee) may take more time.

Related players: Kareem Hunt, Brashard Smith, Clyde Edwards-Helaire

Fantasy Impact:

The Chiefs are coming off their bye and so it's not a great sign that Pacheco isn't ready to go. Hunt should be the team's main back with the rookie Smith likely getting a few more touches, perhaps especially in the passing game. There was even an Edwards-Helaire sighting back in Week 9, as the Chiefs continue to recycle running backs.

Texans QB C.J. Stroud still in concussion protocol

Pro Football Talk

2 hours ago

Texans quarterback C.J. Stroud missed Sunday’s comeback win over the Jaguars with a concussion and his status for Week 11 remains unclear on Monday.

Head coach DeMeco Ryans said at a Monday press conference that Stroud remains in the concussion protocol. He will have to clear it in order to play in Nashville against the Titans this week.

Related players: Davis Mills

Fantasy Impact:

Mills played pretty well filling in for Stroud and would have a nice matchup this week if Stroud is unable to return. Stroud didn't look good after a taking a late hit in Week 9's game, and so it's not surprising, based on that, he would need more time. We'll hopefully know more later this week.