Week 5 DraftKings & FanDuel Showdown Strategy: Sunday Night NFL DFS for Patriots at Bills

Oct 04, 2025
Week 5 DraftKings & FanDuel Showdown Strategy: Sunday Night NFL DFS for Patriots at Bills

Week 5 Sunday Night Football features the top two teams in the AFC East in a matchup that has been highly competitive in recent years as the Patriots travel to Buffalo to take on the Bills. The Bills enter the contest as the leading contender in the AFC with a 4-0 record and the highest point differential in the conference. The Patriots are still finding their footing with a second-year quarterback and first-year head coach leading the way.

Many weeks, there are a variety of ambiguous circumstances—mainly injury- or lineup-driven—that allow fantasy players to leverage uncertainty when building showdown lineups. Those opportunities are not as apparent for Sunday’s matchup. However, there is some inherent fragility in each team’s passing game, as target shares among pass catchers on either side of the ball vary widely week to week. This opens opportunities to target low-priced pass catchers for value. The fact that both teams tend to spread their backfield snaps among multiple running backs further broadens the feasible player pool. Therefore, fantasy players should seek to optimize for single-game scenarios by building lineups that would excel in specific game contexts. There is a plethora of potential high-upside value options on this slate, and optimizing for varying game environments should help fantasy players diversify their value targets.

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