Chargers RB Najee Harris set to play in Week 1

Bills WR Khalil Shakir, who suffered a high ankle sprain in practice a month ago, was listed as full participant today on the season's initial injury report. WR Keon Coleman (groin) was limited.

Related Players: Joshua Palmer, Curtis Samuel, Dalton Kincaid

The whole Bills wide receiver room feels like a stay-away to begin the season, but Shakir should sneak himself back into WR3/4 consideration now that he's fully cleared. He'll need some more splash plays to be truly fantasy relevant, but he's in a good situation as a floor play against a Ravens team that could force a shootout. We'll keep an eye on Coleman's status, but he's more of a boom-bust option if he suits up.

Lions TE Sam LaPorta, who missed time in training camp because of injury, isn't listed on the initial injury report, putting him on track to face the Packers.

Related Players: Brock Wright, Shane Zylstra

It was a disappointing season —in terms of ADP payoff— for LaPorta last season, but it looks like he'll be a full-go in this divisional matchup to start the year. Consider him an easy top-10 option for Week 1.

Kyle Shanahan said he expects Jauan Jennings to play on Sunday. He's limited in today's practice with a calf injury.

Related Players: Ricky Pearsall, George Kittle, Marquez Valdes-Scantling, Skyy Moore

Good news for Jennings managers, but we would have liked to hear this clearance more than a few days away from kickoff. Pearsall could easily begin the season as the target leader for the 49ers, with Kittle being in the running for overall TE1 to begin the year.