49ers RB Matt Breida leaves with shoulder injury

49ers running back Matt Breida left the first preseason game with a shoulder injury and did not return.

Fantasy Impact: 

This would be a fairly significant injury, fantasy-wise, as Breida is expected to be closer to a 1B than a true No. 2 back to Jerick McKinnon this year. If he misses any time, it could leave McKinnon in a true workhorse role, or open up some touches for 2017 draft pick Joe Williams.

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Aidan O'Connell
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