49ers QB Jimmy Garoppolo (ankle) sideline indefinitely

Chiefs WR Hollywood Brown has received final clearance to practice, paving the way for him to play before the regular season ends.

Brown, who is recovering from surgery to repair his SC joint, should have his window opened Friday or Monday. The team will be cautious.

Related Players: DeAndre Hopkins, Xavier Worthy, JuJu Smith-Schuster, Justin Watson

If Brown were cleared by Week 17, he would be incredibly tough to start in pretty much any sort of fantasy league with Championships on the line. However, he could be an interesting click for Playoff-only leagues if he can ramp up in time.

For a second straight day today, Seahawks RB Kenneth Walker III didn’t practice due to his calf injury.

Related Players: Zach Charbonnet, Kenny McIntosh

Looks like things should be cleared out for Charbonnet once again in what could be a very close game against the Packers. If Walker misses Week 15, fire Charbs up as a high-end RB2.

In Week 15, the red and gold have defensive lineman Nick Bosa and linebacker Dre Greenlaw active and ready for the team's second meeting with their NFC West rival, the Los Angeles Rams.

On the other side of the ball, the 49ers will have rookie running back Isaac Guerendo available against the Rams. He was listed as questionable on Wednesday on account of a foot sprain but was given the green light to play ahead of "Thursday Night Football."

Related Players: Patrick Taylor, Israel Abanikanda, Kyle Juszczyk, Ke'Shawn Vaughn

We do expect Guerendo to handle the majority workload for TNF, but you do have to wonder if he gets the same type of workload he would have, had he avoided the injury report all week. Consider him closer to an RB3 than a locked-in RB2 he otherwise would have been.