Week 13 vs. Indianapolis Colts
With game script predictably swinging back in his favor in Week 12, Derrick Henry trampled the lowly Panthers for 76 rushing yards and two touchdowns on 18 carries. Henry has had some volatile production this year, but it is highly correlated to game script and the Titans' team performance. The Titans are small underdogs against the Colts this week, but Indy is atrocious in limiting production by opposing backs as they rank as the third-best matchup in the NFL according to our schedule-adjusted fantasy points allowed metric. With the game projected to be close and the matchup indicating the Titans should be able to run the ball with success, Henry finds himself back in the RB1 ranks for Week 13.