Drew Brees (ribs) placed on Injured Reserve

49ers will start Mac Jones at QB vs Rams

OUT
WR Ricky Pearsall
QUESTIONABLE
QB Brock Purdy
DT Alfred Collins
DT Kalia Davis
LB Dee Winters
LB Tatum Bethune
DL Keion White

Related Players: Jauan Jennings, Kendrick Bourne, Demarcus Robinson, Jordan Watkins

Jones is once again in SuperFlex starting range, but can be looked over for better plays in typical leagues.

Jennings is in WR3 range, but George Kittle is the only other pass-catcher we should trust in fantasy.

Bowles ruled out four players for Sunday vs. Patriots: WR Chris Godwin, RB Bucky Irving, OLBs Haason Reddick and Markees Watts.

Related Players: Rachaad White, Sean Tucker, Emeka Egbuka, Tez Johnson

With both players missing, White should be in line for another RB2 week, Johnson is an interesting WR3/4, and Egbuka is once again a WR1.

Jaguars wide receiver Brian Thomas Jr. will miss Sunday’s game vs. the Texans due to his high ankle sprain.

Related Players: Parker Washington, Jakobi Meyers, Dyami Brown

Lots of moving pieces in the Jaguars' WR room the past couple of weeks.

Jakobi Meyers could be thrust into a larger role than we would have assumed after just a few days with the team.

With Thomas missing Week 10, both Meyers and Washington could end up being desperation WR4 options, but against the Texans, you should hopefully have better options at your disposal.