The Chiefs are ruling out RB Isiah Pacheco, LB Drue Tranquill, DB Bryan Cook, and OT Donovan Smith for their game against the Bills.
This was a fantastic spot for Pacheco, which makes this hurt even more as we head into the final week of almost every fantasy league's regular season. Pacheco has been locked in as the first option in the backfield this season, so we don't have many data points to pull from while predicting the Week 14 rotation.
With that said, we should expect Clyde Edwards-Helaire to get a majority of the short-yardage and goal line work, while Jerick McKinnon —if healthy— figures to get a ton of the passing game work, which should make him very valuable in PPR leagues. It's worth mentioning that the team will be pulling rookie Deneric Prince from the practice squad again. He can be added to teams with deep benches, in case the Pacheco injury hangs around through the fantasy playoffs.