DraftKings & FanDuel NFL DFS Week 6 Cash Strategy & Picks

Oct 10, 2025

Steven Bisig-Imagn Images

Whether you are interested in turning $1 into $1.80 or $50 into $90, deploying a sound cash game strategy when you are building your lineup for Sunday main slates is crucial. Cash game fantasy grinders can run into pitfalls when they fail to recognize the main goal of cash games is to maximize median and beat, often, a small group of opponents (or maybe just one) in the quest to do so.

Ceiling outcomes should be narrowly considered relative to maximizing your lineup’s projectable floor. You can save those high-upside strategies for the $1 million dollar to first place contests on DraftKings or FanDuel, where you should focus on trading median for things like leverage, correlation, and low duplication. In cash games, there’s no reason to shy away from the player with 10x point-per-dollar value just because “everyone else is playing” him. If everyone else is playing him, it is probably a good indication that the market is aware of significant value.

4for4 has all the tools available to help you build your cash game lineups. This article is merely one of them. In the quest to grind out a solid edge (58%-62% win rates is very favorable), the most important tools at your disposal are mean projections, median projections, projection variance, point-per-dollar value, and a way to piece it all together (an advanced calculator is one option).

My goal for this weekly article is to consolidate all the crucial insights from our tools that can be used to gain an edge over your cash game opponents and help you put it all together to build lineups that have positive expected value.

Slate Context

As the Week 6 main slates approach, the crazy outlier value plays become less common as depth charts normalize. Outside of one-off injuries that push backups into starting roles, usage is stabilizing, projections are more predictable, and inputs are less volatile. As expected values become increasingly grounded in concrete data, we can trust the projections more and rely on intuition less. There’s still a balance: continuing to peel back the onion on how projection inputs work—and where they’re fragile—will be crucial to identifying which players offer favorable median outcomes and should be core to your DraftKings and FanDuel cash builds.