Week 17 vs Arizona Cardinals
If sane coaching decisions prevail and Todd Gurley is rested in a meaningless Week 17 matchup, Malcolm Brown could benefit. While Brown had only two games with double-digit rushing attempts, he did finish as an RB1 in Week 1 against the 49ers, with 53 yards on 11 touches. With rookie running back Darrell Henderson on IR, Brown won't have to share the potential workload, though the Rams could promote John Kelly from the practice squad.

The Rams face a Cardinals defense that's giving up the third-most aFPA to running backs, and Vegas is giving this matchup the highest implied point total on the slate at 49 points. The Rams are projected to be responsible for 28 of those points, and if Brown's Week 1 usage is any indicator, he should see plenty of red zone touches. At $4,100 on DraftKings and $4,900 on FanDuel, Brown's matchup makes him an interesting DFS target in Week 17.