This story and other reports say Barkley is also unlikely to play in Week 6 because of his high ankle sprain, leaving the RB duties to Hilliman against a Patriots defense that's allowing just 6.8 points per game this season. While the workload could be there for Hilliman, it's not a safe matchup.
The tweet went on to say its still expected to be too early for medical clearance despite returning to practice last week. It has been 16 days since he suffered a high ankle sprain. With Gallman likely out as well (concussion), the RB duties could fall mostly to Hilliman in a not-so-great matchup against the Pats.