With Rob Kelley likely out this week against the 49ers, Samaje Perine is next in line and "expected to receive a larger role. Head coach Jay Gruden said Perine will likely "get the majority of the carries."
Chris Thompson will still serve as the team's third-down back/passing game specialist out of the backfield, but Perine is in line for first- and second-down work. That would make him an appealing RB2/Flex play, which is where we have him ranked in standard leagues, as our No. 25 RB on the week. In PPR leagues, Perine is our No. 31 RB, while Thompson is ranked as our No. 15 PPR back.