Ben Roethlisberger will not play

Mike Tomlin on Jaylen Warren:

"His progress has been very evident and he's to be congratulated ... Certainly he'll be our featured runner. Certainly you'll see [Kaleb Johnson/Kenneth Gainwell], but at what time and at what degree [will depend week-to-week]."

Warren just signed an extension with the Steelers for two years and now looks to be the Steelers RB1. Warren isn't the biggest back so there will be questions about his size and handling a full workload, but it's good news for his owners who snagged him later in drafts. Johnson should be able to earn some early down work at some point, but it sounds like that will vary. It's just another RB situation that will need to work itself out before fantasy owners feel comfortable.

Hunter Renfrow is listed as one of the starting wide receivers for the Panthers.

Related players: Tetairoa McMillan, Xavier Legette, Jalen Coker, David Moore

Renfrow was cut from the team and then brought back this weekend after Coker moved to IR. It's quite a fall and rise situation for Renfrow, who could find himself as a fantasy producer, with the upside being Adam Thielen-like from last season.

Chargers running back Najee Harris appears poised to play on Friday against the Chiefs.

Harris was listed as a full participant in today’s Chargers practice report as he continues to recover from the Fourth of July eye injury that has held him back for nearly two months.

Coach Jim Harbaugh said Harris has been cleared to play by the Chargers’ medical staff, and Harris himself insisted that the injury is superficial and did not affect his vision.

Related players: Omarion Hampton, Hassan Haskins

Harris looks likely to play Friday night against the Chiefs, which will put a damper on Hampton's Week 1 fantasy value. Both Harris and Hampton are likely to get their share of work in this game, but it remains to be seen how that workload is split up. Both should be considered flex options at this point.