Squirrel Patrol's Week 1 NFL Main Slate DFS GPP Picks

Sep 11, 2026
Squirrel Patrol's Week 1 NFL Main Slate DFS GPP Picks

Week 1 brings a 12-game main slate after the season opened with games on Wednesday and Thursday night. With no in-season data yet, pricing, Vegas lines, and the prop market carry more of the load than usual.

Only one game on the slate carries a total above 50 points, with TB/CIN at 50.5 and the Bengals favored by 3.5. NO/DET is right behind at 49.5, with the Lions favored by 7.0, and three games share the next-highest total at 47.5 (BAL/IND, ARI/LAC, and CHI/CAR). NYJ/TEN has the lowest total on the slate at 38.5. The Chargers carry the highest implied team total at 28.5 as 9.5-point favorites over Arizona, with the Lions (28.25) and Bengals (27.0) next.

Let's break down the positions, spotlight some of the best DFS options, and map out a path to the top of the leaderboards this Sunday.

Quarterbacks

You’re Missing Out
Get access to this article and all our DFS and season-long tools and rankings:
  • DFS & Season-Long Content
  • Lineup Generator
  • Optimal Cash & GPP Lineups
  • Floor & Ceiling Projections
  • -Leverage Scores
  • -...and much much more!
Already a subscriber? Log in?
Latest Articles
Most Popular